Mammography and clinical breast examination are the two major techniques used to screen for breast cancer. However, as true for any screening test, they are not completely accurate. If it is determined, based on mammographic findings, that there is a possibility of breast cancer, this is usually confirmed or disconfirmed by a subsequent biopsy. A false positive test is a mammogram positive test that is disconfirmed by biopsy. The data in Table 1 were reported in a paper concerning breast cancer screening (Elmore, et al, New England Journal of Medicine 1998; 338(16): 1089-1096). Table 1 False positive breast cancer screening tests over a 10-year period # Screening tests # False positive tests 9762 631 1. Another aspect of mammographic screening is the presence of false negatives. A false negative is a screen negative woman who has breast cancer. False negatives usually occur because the tumors are small and hard to detect. It is estimated that among women with breast cancer, 2% of all screening tests are false negatives. Suppose that there are 100 women who have breast cancer. What is the probability that at least 3 of them will not be detected by a mammogram?

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Mammography and clinical breast examination are the two major techniques used to screen
for breast cancer. However, as true for any screening test, they are not completely accurate.
If it is determined, based on mammographic findings, that there is a possibility of breast
cancer, this is usually confirmed or disconfirmed by a subsequent biopsy. A false positive test
is a mammogram positive test that is disconfirmed by biopsy. The data in Table 1 were
reported in a paper concerning breast cancer screening (Elmore, et al, New England Journal
of Medicine 1998; 338(16): 1089-1096).
Table 1 False positive breast cancer screening tests over a 10-year period
# Screening tests
# False positive tests
9762
631
1. Another aspect of mammographic screening is the presence of false negatives. A false negative
is a screen negative woman who has breast cancer.
False negatives usually occur because the tumors are small and hard to detect. It is estimated
that among women with breast cancer, 2% of all screening tests are false negatives.
Suppose that there are 100 women who have breast cancer. What is the probability that at least
3 of them will not be detected by a mammogram?
Transcribed Image Text:Mammography and clinical breast examination are the two major techniques used to screen for breast cancer. However, as true for any screening test, they are not completely accurate. If it is determined, based on mammographic findings, that there is a possibility of breast cancer, this is usually confirmed or disconfirmed by a subsequent biopsy. A false positive test is a mammogram positive test that is disconfirmed by biopsy. The data in Table 1 were reported in a paper concerning breast cancer screening (Elmore, et al, New England Journal of Medicine 1998; 338(16): 1089-1096). Table 1 False positive breast cancer screening tests over a 10-year period # Screening tests # False positive tests 9762 631 1. Another aspect of mammographic screening is the presence of false negatives. A false negative is a screen negative woman who has breast cancer. False negatives usually occur because the tumors are small and hard to detect. It is estimated that among women with breast cancer, 2% of all screening tests are false negatives. Suppose that there are 100 women who have breast cancer. What is the probability that at least 3 of them will not be detected by a mammogram?
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