MATLAB: An Introduction with Applications
6th Edition
ISBN: 9781119256830
Author: Amos Gilat
Publisher: John Wiley & Sons Inc
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It is hypothesized that there are fluctuations in norepinephrine (NE) levels which
accompany fluctuations in affect with bipolar affective disorder (manic-depressive
illness). Thus, during depressive states, NE levels drop; during manic states, NE levels
increase. To test this relationship, researchers measured the level of NE by measuring the
metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG in micro gram per 24 hour) in the
patient's urine experiencing varying levels of mania/depression. Increased levels of
MHPG are correlated with increased metabolism (thus higher levels) of central nervous
system NE. Levels of mania/depression were also recorded on a scale with a low score
indicating increased mania and a high score increased depression. The data is provided
below.
MHPG Affect
980 22
1209 26
1403 8
1950 10
1814 5
1280 19
1073 26
1066 12
880 23
776 28
a. Can MHPG significantly predict affect? Please support your answer.
b. Please report the regression equation and then interpret the following:
i. Slope –
ii. Intercept –
iii. R (squared)
c. Increases in MHPG cause increases in affect...true or false? Please explain.
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