Is this study experimental or observational? Justify.

Glencoe Algebra 1, Student Edition, 9780079039897, 0079039898, 2018
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ISBN:9780079039897
Author:Carter
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Chapter10: Statistics
Section10.6: Summarizing Categorical Data
Problem 30PPS
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Is this study experimental
or observational? Justify.
Transcribed Image Text:Is this study experimental or observational? Justify.
Vitamin E and the Risk of Prostate Cancer: Klien et al (2011) conducted the
following study to determine the effect of vitamin E and selenium treatment on
the risk of developing prostate cancer in healthy men. A total of 34,887 men
from different study sites in the United States, Canada, and Puerto Rico were
randomly selected. To be eligible to participate, the men had to take a rectal
examination that showed he was not suspicious of having prostate cancer and
be aged 50 years or older for black men and 55 years or older for all others.
Each man was randomly assigned to receive one of four treatments: selenium,
vitamin E, selenium and vitamin E together, or a placebo. The men were
followed up after 8 years to see if they had developed prostate cancer or not.
The main question of interest is to determine if the risk of developing prostate
cancer differs by the treatment taken. The data are summarized in the table
below:
No Prostate Cancer Prostate Cancer
Total
Selenium
8,752
8,737
8,702
8,696
34,887
8177
575
Vitamin E
8117
620
Selenium and Vitamin E
8147
555
Placebo
8167
529
Total
32,608
2,279
Transcribed Image Text:Vitamin E and the Risk of Prostate Cancer: Klien et al (2011) conducted the following study to determine the effect of vitamin E and selenium treatment on the risk of developing prostate cancer in healthy men. A total of 34,887 men from different study sites in the United States, Canada, and Puerto Rico were randomly selected. To be eligible to participate, the men had to take a rectal examination that showed he was not suspicious of having prostate cancer and be aged 50 years or older for black men and 55 years or older for all others. Each man was randomly assigned to receive one of four treatments: selenium, vitamin E, selenium and vitamin E together, or a placebo. The men were followed up after 8 years to see if they had developed prostate cancer or not. The main question of interest is to determine if the risk of developing prostate cancer differs by the treatment taken. The data are summarized in the table below: No Prostate Cancer Prostate Cancer Total Selenium 8,752 8,737 8,702 8,696 34,887 8177 575 Vitamin E 8117 620 Selenium and Vitamin E 8147 555 Placebo 8167 529 Total 32,608 2,279
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