Is there a possibility that by manipulating the microenvironment, we could disrupt the signals controlling the phenotype of cancer (stem?) cells.
Q: a way in which proto-oncogenes can change to become genes that induce cancer?
A: A proto-oncogene is a normal gene that can turn into an oncogene due to mutations or increased…
Q: Should genetic testing for cancer be availablefor everyone, or should genetic testingbe confined to…
A: Cancer is an abnormal proliferation of body cells that has undergone mutation. The cancer is of…
Q: Proto-oncogenes can be converted to oncogenes in a number of different ways. In some cases, the…
A: Cancer is a disease that is associated with uncontrolled division of cells and invasion of…
Q: researchers identified the important role of GNAQ in both development and cancer
A: GNAQ is G Protein subunit Alpha Q.It is a protein coded gene present on chromosome 9.It is a guanine…
Q: they argued that promoter switching may be correlated with cancer development and progression…
A: A DNA (deoxyribonucleic acid) sequence where the protein binds and initiates the transcription of…
Q: ene therapy approaches have been studied for cancer gene therapy. These approaches include? (select…
A: Cancer Cancer is a serious disease marked by an abnormal and uncontrolled cell division of cells…
Q: Why is this system promising in curing cancer and genetic diseases? What are some of the…
A: Introduction Gene therapy involves changing the genetic instructions within a person's cells to…
Q: Which of the following is a method to reprogram a cell to de-differentiate fibroblast into a…
A: De-differentiation of fibroblast cells into pluripotent stem cells.
Q: You found a protein called X in colon cancer patients that is over-expressed and is associated with…
A: Metastasis is the process by which cancer cells spread from the primary tumor site to other parts of…
Q: B. Briefly describe how can RNA seq be used to quantify differential gene expression between two…
A: It is attainable by performing RNA-Seq with spike-ins, samples of ribonucleic acid at identified…
Q: Give two examples of how genomic studies have altered our understanding of cancers.
A: Cancer was initially described by Hippocrates when he identified two forms of cancer: ulcer forming…
Q: Which of the following must scientists understand in order to create effective cancer treatments?…
A: Effective cancer treatment in the order of b a d c. b. Where cancer originated : Scientists first…
Q: Can cells with your personal genome be reprogrammed for new therapies?
A: Yes.
Q: 3. Figure on the right shows a DNA microarray assay of gene expression levels. In this microarray if…
A: Micro arrays are utilised for the determination of gene expression patterns in specific tissues or…
Q: 6. _____ is a DNA sequence. 1.Coactivator 2.Corepressor 3.Enhancer 4. Inducer…
A: Deoxyribonucleic acid or DNA is a genetic material present in each and every individual that…
Q: many cancers have mutations in more than one of these genes how could this happen. how did a single…
A: Cancer or tumor results when there is a normal cell division and there is no control on the cell…
Q: Discuss the interplay between genetics and environment in the development of cancer (it would be…
A: Research on several diseases have found that the cause of diseases are not only environmental or…
Q: List the 5 ways genes can be converted to cancer causing genes.
A: Cancer is a complex disease that leads to the uncontrolled cell division. It can be occurs by…
Q: Some germ-line mutations predispose individuals tocancer, yet often environmental factors…
A: A germline mutation is also called a germinal mutation. It refers to identifiable changes in the…
Q: Are genome and karyotype instabilities consequencesor causes of cancer?
A: Genome ad karyotype instabilities really leads to cancer.Lets have a detailed discussion: Genome…
Q: How are DNA microarrays used to screen a patient’s cells for a cancer prognosis?
A: DNA microarrays is an advanced technique to study the expression the genes at once.
Q: The "initiation" stage of cancer refers to: a) The stage where DNA is mutated, and permanent…
A: Introduction : Cancer is defined by the following characteristics: • Uncontrolled…
Q: Can the proteomic fingerprint help determine if a given cancer is resistant or sensitive to a…
A: Proteomic fingerprint is an approach that depends on the patterns of the proteins observed but…
Q: Do more mutations necessarily mean that more cancer-causing genes are faulty? Why or why not?
A: Biotechnology is a wide range of studies where it uses its techniques with biological systems to…
Q: terms of genetics --- What is cancer, how is it initiated, maintained
A: Cancer develops when the body's normal control mechanism stops working. Old cells do not die and…
Q: Explain the advantage of the systems biology approachto studying cancer versus the approach of…
A: System biology is used in the preparation of complex biological systems based on the interactions…
Q: Despite the failure to date of gene therapy, identification of the gene responsible for cystic…
A: Cystic fibrosis (CF) is a genetic disease caused by a mutation in the CFTR (cystic fibrosis…
Q: Give a possible explanation for why a mutation in a single gene does not always lead to cancer.
A: Mutation in a gene is defined as any change or alteration in the structure, and hence, function of…
Q: what is the role of TERF2 in the deregulation of CDKN1A gene to cause cancer.
A: The basic unit of heredity is the gene, which is a DNA region that codes for a specific protein.…
Q: Describe and explain the epidemiological evidence supporting the view that cancer develops through a…
A: Note- as we are allowed to do only one question at a time. Kindly repost the other question…
Q: There are three broad categories of cancer-related genes: proto-oncogenes, tumor suppressor genes,…
A: It is an uncontrollable cell division that get metastasized into surrounding tissues.
Q: Sometimes, malignant cells do not stay properly anchored in tissues because of the loss of function…
A: Malignancy It refers to the presence of cancerous cells that have the ability to spread to other…
Q: Mutations in the BRCA genes have been shown to be related to a higher incidence of breast cancer in…
A: BRCA is a gene that produces proteins that help repair damaged DNA. everyone has two copies of the…
Q: In 2013 the actress Angelina Jolie elected to have prophylactic double-mastectomy surgery to prevent…
A: Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when…
Q: In a recent study, scientists used gene editing to treat both sickle cell disease and…
A: Sickle cell disease and beta thalassemia are genetic disorders caused by errors in genes of…
Q: hat risk factors exist that make individuals more susceptible to this type of disease? Are there any…
A: Abnormal cell growth with the potential to invade or spread to other parts of the body, that group…
Q: Which are ethical concems related to editing the genes of germline cells? Select all that apply. The…
A: Genetics is the branch of biology that deals with the study of genes, their variation, and heredity…
Q: Which of the following is an enabling characteristic for cancer that can increase the likelihood of…
A: The somatic mutations in the genome of a cancer cell, irrespective of their structural nature, can…
Q: Explain how our understanding of the molecular basis of cancer has been used to develop new…
A: Hippocrates a Greek physician described cancer as ulcer-forming and non-ulcer-forming carcinoma,…
Q: Why are the proteins called p53 and Ras studied so much these days?
A: P53 and Ras, both proteins are involved in the cancer mechanism. Cancer is a condition in which the…
Q: Is it correct to say that the palladin gene causes cancer?
A: This palladin gene encodes a cytoskeletal protein that is required for organizing the actin…
Q: What are the key steps of transformation, tumorigenesis and metastasis on a cellular and tissue…
A: Transformation is a process in which a normal cell is transform into a cancerous cell Tumor genesis…
Q: Imagine you have used cBioportal and breast cancer patient datasets and identified a…
A: Introduction :- Cancer is defined as the uncontrolled and un-regulated proliferation of cells , due…
Q: what are the rolls that the p53 gene and RAS protein take on when trying to stop a cancer cell from…
A: Given: Role of p53 and RAS protein to stop a cancer cell from replication. What happens if mutation…
Is there a possibility that by manipulating the microenvironment, we could disrupt the signals controlling the
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- How can researchers pinpoint the particular driver mutations most responsible for the cancer phenotype?Because cancer cells do not normally die, does this imply that if people attempted to extend their lives, it would most likely be through the employment of cancer cells? Could cancer be used as a vector to modify cells or shape it into what is desired?what are the rolls that the p53 gene and RAS protein take on when trying to stop a cancer cell from further replicating. Also, what would happen if a mutation were to occur in both genes?
- Our understanding of the molecular biology of cancer formation has been greatly enhanced by studying oncogenic viruses. Answer the following questions regarding oncogenic retroviruses? Explain how a gain of function mutation in the Ras protein caused by a retrovirus might lead to cancer formation.Here, Research a cancer caused by an oncogenic virus. how the virus disrupts normal cell function and causes cancer to develop. What risk factors exist that make individuals more susceptible to this type of disease? Are there any preventative measures that can be taken to mitigate the risk of contracting this disease? What therapies are available or being developed that combat this disease? what are the methods of action for all therapies available. ?What is/are the role/s of molecular techniques in understanding cancer? Cite some references from the web.
- Figure 17.15 In 2011, the United States Preventative Services Task Force recommended against using the PSA test to screen healthy men for prostate cancer. Their recommendation is based on evidence that screening does not reduce the risk of death from prostate cancer. Prostate cancer often develops very slowly and does not cause problems, while the cancer treatment can have severe side effects. The PCA3 test is considered to be more accurate, but screening may still result in men who would not have been harmed by the cancer itself suffering side effects from treatment. What do you think? Should all healthy men be screened for prostate cancer using the PCA3 or PSA test? Should people in general be screened to find out if they have a genetic risk for cancer or other diseases?Personalized cancer treatments involve identifying specific pathways in an individual tumor and selecting drugs that are effective for the modified pathways. One way to do this is to take culture cells from a biopsy of a specific paient and test the effects of a battery of drugs on the patiets cells in culture. How might heterotypic interactions complicate this strategy? How might cells be cultured differently to minimize these complications (limit 5-6 sentences)?1.create a Graphical Abstract to summarise the role of ALP in cancer?With image
- Hi, can you elaborate about these two concepts: 1) Can telomere inhibition be good cancer treatment? 2) Can cancer steam cells hypothesis be a good / bad approach?The drug pump activity of Cancer stem cells can be explained by the overexpression of: a. Mdr1 b. Muc2 c. MMR d. CYPsWhat are Ras protein and p53? How can mutations in the genes for these proteins contribute to cancer?