Intestinal bacteria convert choline to trimethylamine, and the liver converts this gas to trimethylamine N-oxide (TMAO). TMAO promotes atherosclerosis, possibly by stimulating macrophages to take up LDL. (a) Could this chemistry explain why eating large amounts of eggs (which are rich in phosphatidylcholine) is a risk factor for cardiovascular disease? (b) Some research suggests that ingesting supplemental phosphatidylcholine can slow the aging process. Is this consistent with your answer to Part (a)?

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter7: Basic Clinical Microbiology
Section7.5: Tests For Group A Streptococcus
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Intestinal bacteria convert choline to trimethylamine, and the liver converts this gas to trimethylamine N-oxide (TMAO). TMAO promotes atherosclerosis, possibly by stimulating macrophages to take up LDL. (a) Could this chemistry explain why eating large amounts of eggs (which are rich in phosphatidylcholine) is a risk factor for cardiovascular disease? (b) Some research suggests that ingesting supplemental phosphatidylcholine can slow the aging process. Is this consistent with your answer to Part (a)?

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