Inhibitory postsynaptic potentials cause what type of change at the post-synaptic membrane? Hyperpolarization Depolarization Decreased threshold No change
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- If action potential propagation from one neuron to another neuron requires ACh release, what event at the synaptic cleft explains the need for action potentials to arrive at a high rate before the post-synaptic membrane achieves threshold? the lack of sodium voltage gated channels on the post-synaptic membrane O the rapid breakdown of ACh by ACHE at the synaptic cleft the slow release of ACh by the synaptic vessicles the slow movement of sodium through chemical gates Previous Next MacBook AirA loss-of-function mutation in the ion channel responsible for thegeneration of end-plate potentials results in a diminished permeabilityof the ion channel. 1) How would you experimentally test the effect of the mutation on thefunctional properties of the cell (synapse)? You should discuss the typesof postsynaptic responses and physiological parameters you couldmeasure.Which of the following statements is TRUE about the depolarization phase of action potential? Group of answer choices: Na-K pump initiates depolarization. Potassium ion channels quickly opens to allow efflux of ions. Depolarization is characterized by the movement of calcium ions out of the cell. Depolarization is primarily triggered by opening of sodium ion channels asap pls
- Anatomically, the motor endplate potential is characterized by synaptic boutons active zones junctional folds Ach receptor-channels all the aboveAbsolute refractory periods in axons: Result from conformational changes in voltage gated K channels after opening O Result from Cl channel induced hyperpolarization O Result from Ca dependent phosphorylation of K channels Result from conformation changes in voltage gated Na channels after opening O Result from Ca dependent phosphorylation of Na channelsSynaptic transmission depends upon :- a-direct transmission of impulses from the presynaptic neuron to the postsynaptic neuronb- diffusion of neurotransmitters from synaptic knobs into the soma and dendrites of postsynaptic neuronsc- presence of voltage-gated Ca ++ channels in membrane of synaptic knobsd- presence of voltage-gated Ca ++ channels in the subsynaptic membrane
- Assume the membrane is only permeable to Na+ and K+, the electrical model of axon membrane is the following: Outside A INa gna ENa Ex D Inside The membrane potential at rest and at peak is -70mV and 45mV respectively; the potential of Sodium ion is 60mV and the potential of Potassium ion is -80mV. Find the ratio 9Na at rest and at peak. gKWhat stage of the action potential is illustrated by the set up shown? interstitial fuid axon cytoplasm interstitial fiuid Resting potential Hyperpolarization O Depolarization Repolarization K'charnelWhich of the following is true of ACh (acetylcholine)? O It cannot be degraded within the synaptic cleft to which it was released; it must be internalized and degraded by the cell that receives it O It is always excitatory because it causes the entrance of Na+ into a cell which leads to an increase in intracellular mV O It is released via exocytosis from the axon terminal of a somatic motor neuron O It is released via exocytosis from all pre-ganglionic motor neurons of the ANS
- Action potentials propagate in one direction because of: O K+ Voltage-gated Channels become inactive for a while O Nat Voltage-gated Channels become inactive for a while O K+ nongated Channels become inactive for a while O Nat nongated Channels become inactive for a whileA graded potential that achieves threshold leads to the generation of an action potential. Which one of the following statement/s regarding graded and action potentials is/are true? O graded potentials result from the opening of chemically gated sodium channels O action potentials result from the opening of voltage gated sodium channels O graded potentials result from the opening of calcium gated channels and action potentials result from the opening of sodium gated channels a and b NextIf a post synaptic neuron is stimulated to threshold by spatial summation this implies that the post synaptic cell has a lower than normal threshold the postsynaptic cell has many synapses with many presynaptic neurons the post synaptic cell is getting stimulated many times during a short period of time by a single presynaptic neuron the post synaptic cell is slow to repolarize