Increased ROS levels are a hallmark for Alzheimer's Disease. This is accurately described by all but which of the following statements? ROS production is upregulated because of the activity of the enzyme NADPH oxidase Oxidative phosphorylation is increased, leading to enhanced ROS generation via the ETC Amyloid precursor protein is converted in higher amounts to the amyloid peptide facilitating greater amounts of aggregation BACE1 levels are transcriptionally increased via hypoxia inducible factor Mitochondrial pyruvate flux is reduced
Increased ROS levels are a hallmark for Alzheimer's Disease. This is accurately described by all but which of the following statements? ROS production is upregulated because of the activity of the enzyme NADPH oxidase Oxidative phosphorylation is increased, leading to enhanced ROS generation via the ETC Amyloid precursor protein is converted in higher amounts to the amyloid peptide facilitating greater amounts of aggregation BACE1 levels are transcriptionally increased via hypoxia inducible factor Mitochondrial pyruvate flux is reduced
Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter9: Cell Communication
Section: Chapter Questions
Problem 1VCQ: Figure 9.8 HER2 is a receptor tyrosine kinase. In 30 percent of human breast cancers, HER2 is...
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