Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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In glycolysis, fructose 1,6-bisphosphate is converted to two products with a standard free-
energy change (AG) of 23.8 kJ/mol. Under what cellular conditions will the free-energy
change be negative, enabling the reaction to proceed spontaneously to form products?
O In a cell where the concentrations of products and reactants yield a low value of the mass-action ratio
Q
○ The reaction will not go to the right spontaneously under any conditions because the AG is positive
○ The reaction will proceed spontaneously to the right if there is a high concentration of products
relative to the concentration of fructose 1,6-bisphosphate
○ The reaction will proceed spontaneously to the right if there is a high concentration of enzyme to
catalyze the reaction
O None of these conditions is sufficient
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Transcribed Image Text:In glycolysis, fructose 1,6-bisphosphate is converted to two products with a standard free- energy change (AG) of 23.8 kJ/mol. Under what cellular conditions will the free-energy change be negative, enabling the reaction to proceed spontaneously to form products? O In a cell where the concentrations of products and reactants yield a low value of the mass-action ratio Q ○ The reaction will not go to the right spontaneously under any conditions because the AG is positive ○ The reaction will proceed spontaneously to the right if there is a high concentration of products relative to the concentration of fructose 1,6-bisphosphate ○ The reaction will proceed spontaneously to the right if there is a high concentration of enzyme to catalyze the reaction O None of these conditions is sufficient
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