In electron micrographs of HSV infection, it can be seen that the intact virus initially reacts with cell-surface proteoglycans, then with specific receptors. This is later followed by viral capsids docking with nuclear pores. Afterward, the capsids go from being full to being "empty." Which of the following statements best fits these observations? O The viral envelope is not required for infectivity, since the envelope does not enter the nucleus. The viral envelope mediates entry into the cell, the capsid mediates entry into the nuclear membrane, and the genome is all that enters the nucleus. Only the genetic material of the virus is involved in the cell's infectivity, and is injected into the host cell like the genome of a phage. O Viral capsids are needed for the cell to become infected; since the full capsids enter the nucleus.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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In electron micrographs of HSV infection, it can be seen that the intact virus initially reacts
with cell-surface proteoglycans, then with specific receptors. This is later followed by viral
capsids docking with nuclear pores. Afterward, the capsids go from being full to being
"empty." Which of the following statements best fits these observations?
The viral envelope is not required for infectivity, since the envelope does not enter the
nucleus.
The viral envelope mediates entry into the cell, the capsid mediates entry into the
nuclear membrane, and the genome is all that enters the nucleus.
Only the genetic material of the virus is involved in the cell's infectivity, and is injected
into the host cell like the genome of a phage.
Viral capsids are needed for the cell to become infected; since the full capsids enter the
nucleus.
Transcribed Image Text:In electron micrographs of HSV infection, it can be seen that the intact virus initially reacts with cell-surface proteoglycans, then with specific receptors. This is later followed by viral capsids docking with nuclear pores. Afterward, the capsids go from being full to being "empty." Which of the following statements best fits these observations? The viral envelope is not required for infectivity, since the envelope does not enter the nucleus. The viral envelope mediates entry into the cell, the capsid mediates entry into the nuclear membrane, and the genome is all that enters the nucleus. Only the genetic material of the virus is involved in the cell's infectivity, and is injected into the host cell like the genome of a phage. Viral capsids are needed for the cell to become infected; since the full capsids enter the nucleus.
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