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- Question 16 Which event may lead to cancer? Select all that apply. gene mutation functioning p53 protein Rb protein phosphorylating Improper replication of DNA during synthesis faulty DNA repairQuestion 29 A gene that codes for a receptor for a growth factor is mutated. A normally functioning receptor binds with a growth factor and then sends a signal into the cell. However, the abnormal receptor sends a constant signal into the cell whether or not it binds with the growth factor. The gene that codes for the abnormal receptor is . an oncogene a tumor benign a tumor suppressor gene metastatic Question 30 BRCA1 and p53 are both examples of ________ suppressor genes, which normally act to prevent cell division. Question 31 Match the following mutation types with their description. Mutation that results in the creation of a stop codon [ Choose ] Silent mutation Nonsense nutation Missense mutation Frameshift mutation Mutation that encodes the same gene as the original gene [ Choose ] Silent mutation Nonsense nutation Missense mutation Frameshift mutation…QUESTION 4 The main advantage of an established cell line versus primary cell line prepared directly from tissue is: Othey can divide indefinitely (immortalized) Othey may have different properties than source tissue Othey can display differentiated state of source tissue Ⓒlarge numbers of cell can be produced QUESTION 5 Velocity centrifugation separates cellular components by while equilbrium centrifugation separates them by — O size and shape, density Odensity, size and shape O size, shape Oshape, size
- O Tumors of the blood A tumor with limited growth Explain why radiation and 5-fluorouracil are effective cancer treatments. Please include a few sentences about how these treatments interact with the cell cycle. Your answer Any comments please use this space (e.g. to clarify an answer or point o issues on questions, etc.)D Question 18 Your patient's biopsy report indicates they have "cancer in situ". This means: Abnormal cells are present, they have not invaded local cells O Cells are normal, they will become cancer cells in the near future Abnormal cells are present, they have invaded a small number of local cells Cells are normal, they will not become cancer cells unless stimulated « PreviousDid Steve Job's cancer metastasize during the nine months he tried holistic treatments rather than surgery? No, it had already metastasized No, it metastasized after his surgery O No, the surgery caused it to metastasize O Yes, this is when it metastasized
- QUESTION 3 As mentioned in the lecture, both excessive and insufficient apoptosis can cause problems. If scientists wanted to develop a drug to inhibit apoptosis in C. elegans, which of the following would be likely to produce that effect? (Select ALL correct answers) A drug that inhibits Ced-9 A drug that inhibits Ced-4 A drug that inhibits Ced-3 A drug that interferes with death-signaling receptorsQuestion 15 Cell differentiation in most animals results in O The building of the many tissues of the body O Three body layers O All of the above O The formation of endoderm, mesoderm and ectoderm tissues O Cells shutting some gene books and opening othersQuestion 60 What are oncogenes? specific to males mutated variants of genes that code for cell division tumor suppressor genes genes that code for proteins which stop the cell cycle Question 61 Homologous chromosomes undergo recombination during prophase II. metaphase I. metaphase II. both prophase I and II. prophase I. Question 62 List three alterations that occur before mRNA leaves the nucleus for translation. Question 63 Webbing of digits (fingers) in humans, or syndactyly, typically occurs during the sixth to eighth weeks of embryonic life. One of every 2000–2500 births have syndactyly, and it is more common among Caucasian males. Syndactyly is caused by the failure of what process? cell division mitosis cytokinesis apoptosis Question 64 Arrange the following structures in order from smallest to largest? Gene, chromosome, genome, nucleotide Question 65 Which of the following is FALSE about telomeres? telomeres are repeats of a specific DNA sequence telomeres shorten…
- QUESTION 5 Assuming mitosis is divided into prophase, prometaphase, metaphase, anaphase, and telophase, identify the events that take place in metaphase. The chromosomes move toward the equator by action of the kinetochore microtubules. The nucleolus disappears. U Centrioles replicate. The nuclear envelope disappears. Microtubules attach to kinetochores. All chromosomes are aligned on the metaphase plate. Sister chromatids split. Chromosomes condense. Spindle fibers form. Centrioles are migrating to opposite sides of the nucleus. QUESTION 6 Assuming mitosis is divided into prophase, prometaphase, metaphase, anaphase, and telophase, identify the events that take place in anaphase. Centrioles are migrating to opposite sides of the nucleus. Chromosomes decondense. The nuclear envelope reforms. The chromosomes move toward the equator by action of the kinetochore microtubules. All chromosomes are aligned on the metaphase plate. The nucleolus disappears. Sister chromatids split. Kinetochore…QUESTION 5 Which of the following puts the stages of mitotic cell division in the order that they happen in? anaphase, cytokinesis, interphase, metaphase, prophase, telophase O A. interphase, prophase, metaphase, anaphase, telophase, cytokinesis O B. cytokinesis, prophase, metaphase, anaphase, telophase, interphase O D. interphase, metaphase, anaphase, prophase, telophase, cytokinesis QUESTION 6 What would be the result of a mitotic cell division of a cell with 46 chromosomes? A. a cell with 92 chromosomes B. two cells with 46 chromosomes each C. two cells with 23 chromosomes each D. four cells with 23 chromosomes eachQUESTION 7 Match the stage of mitotic cell division with its description. v chromosomes line up in the middle of the cell on spindle fibers cytoplasmic division results in two new cells A. metaphase sister chromatids separate and daughter chromosomes begin moving to opposite poles B. cytokinesis C. prophase nuclear membrane disintegrates, DNA condenses, spindle highways begin to be formed D. telophase E. anaphase F. interphase daughter chromosomes arrive at opposite ends of the cell, the cell membrane pinches in, nuclear membranes form DNA replication and organelle doubling