Huntington disease is a rare dominant condition in humans that results in a slow but inexorable deterioration of the nervous system. The disease shows what might be called age-dependent penetrance, which is to say that the probability that a person with the Huntington genotype will express the phenotype varies with age. Assume that 50% of those inheriting the HD allele will express the symptoms by age 40. Susan is a 35-yearold woman whose father has Huntington disease. She currently shows no symptoms. What is the probabbility that Susan will show symptoms in five years?

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Q: Marfan syndrome is a disease caused by a rare dominant allele of the fibrillin-1 gene. Fibrillin-1…

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A: 50 percent chances.

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A: A Y linked trait because the defect occurs only in males.

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A: For this we will use binomial expression  P = n!/ x! (n-x!) * pxq(n-x)

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A: I) Origin of bombay blood group  is in Mumbai in 1952.

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A: X Linked Inheritance When the disease-causing gene or allele is present on the Sex chromosome…

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Q: Hemophilia A is an X-linked trait where blood clotting is affected due to a mutation in a clotting…

A: Hemophilia is a genetic disorder which slows down the process of blood clotting. It is X linked…

Q: Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an…

A: Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an…

Q: Huntington disease (HD) is a genetic disorder that usually first appears in middle age and, over…

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Q: show effects of the allele under some circumstances (refer to the linked article and Mendelian…

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Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.