Huntington disease is a rare dominant condition in humans that results in a slow but inexorable deterioration of the nervous system. The disease shows what might be called age-dependent penetrance, which is to say that the probability that a person with the Huntington genotype will express the phenotype varies with age. Assume that 50% of those inheriting the HD allele will express the symptoms by age 40. Susan is a 35-yearold woman whose father has Huntington disease. She currently shows no symptoms. What is the probabbility that Susan will show symptoms in five years?

Q: Huntington's disease is a very rare, debilitating disease that affects approximately 1 in 10,000…

A: Autosomal genetic disorder is controlled by autosomes and X-linked genetic disorder is controlled by…

Q: Familial hypercholesterolemia (FH) is an inherited disorder in humans that is incompletely dominant.…

A: Alleles are the alternative forms of a gene that are located on the same locus of a homologous…

Q: wo forms of hemophilia are determined by genes on the X chromosome in humans. Assume that a…

A: Hemophilia is an X-linked recessive disease characterized by the lack of normal blood clotting due…

Q: Phenylketonuria (PKU) is an autosomal recessive disease that results from a defect in an enzyme that…

A: Phenylketonuria is an inborn error of metabolism which happened due to decreased or low metabolism…

Q: One parent with the Achondroplasia phenotype and a normal parent have 2 children. Both children have…

A: Achondroplasia is a type of osteochondrodysplasia in which the cartilage at the ends of the limb…

Q: X-linked lissencephaly is an X-link dominant trait pertaining to a brain disorder. It superficially…

A: Given information Lissencephaly is an X-linked dominant trait Mr. Panganiban is affected by the…

Q: The allele for albinism is recessive to the allele for normal skin pigmentation. All individuals who…

A: An inherited disorder that presents with little or no melanin production, which results in either…

Q: Male-pattern baldness is an example of a sex-influenced trait. The baldness allele, which causes…

A: Option b NN x BN

Q: Julie (a female) has hemophilia. Based on this information, what can we say about the genotypes of…

A: Introduction X-linked diseases are those that occur due to the presence of abnormal/ diseased…

Q: A woman who is eight (8) weeks pregnant requests a direct test for Huntington’s disease on her…

A: Huntington's disorder is an autosomal dominant genetic disorder. It causes the breakdown of the…

Q: The father of three sons and two daughters begins to show symptoms of Huntington's disease. What is…

A: The mode of inheritance is a pattern of obtaining parentral alleles  or genes to the offsprings. The…

Q: Sickle cell anemia is a genetically inherited autosomal recessive trait in which results in a…

A: According to Hardy Weinberg`s equilibrium p2 + q2 +2pq =1 and p+q=1 p = frequency of the dominant…

Q: Describe the genetics of Huntington's Disease (choose all that are correct): X-linked…

A: Answer -  AUTOSOMAL DOMINANT RARE Huntington's disease is an autosomal dominant disorder.…

Q: A form of hemophilia is caused by a sex-linked (X-linked) recessive gene. A phenotypically normal…

A: 50 percent chances.

Q: Duchennnes’s muscular dystrophy is caused by a rare sex-linked allele and usually

A: Here , Duchennnes’s muscular dystrophy is X-linked recessive disease. Here given that mother's…

Q: results from an autosomal dominant gene in some families. Females who carry the gene show no…

A: A Y linked trait because the defect occurs only in males.

Q: Cystic fibrosis is a disease that is passed down through the generations. The recessive alleles for…

A: Genes carry the traits from one generation to another. Genes that code for different forms of a…

Q: Review the process of autosomal dominant inheritance by coloring the following figures. In this…

A: According to the question, we have to review the process of autosomal dominant inheritance by…

Q: The father of five children begins to show symptoms of huntington disease. what is the probability…

A: Huntington disease is a type of genetic disorder that is characterized as a non-dominant disorder…

Q: When phenylalanine is converted to phenylpyruvic acid, this molecule accumulates in the body and…

A: For this we will use binomial expression  P = n!/ x! (n-x!) * pxq(n-x)

Q: Wilma and Wally have one male child who has been diagnosed withDuchenne muscular dystrophy, an…

A: Duchenne muscular dystrophy is a medical condition of muscular dystrophy which is caused by DMD gene…

Q: Huntington disease is a rare dominant condition in humans that results in a slow but inexorable…

A: Huntington disease is an inherited neural disorder that causes the death of brain cells. The…

Q: Classical hemophilia is a sex-linked disease caused by a recessive gene on the X chromosome.…

A: Hemophilia is a X linked recessive trait.  Let X allele encodes normal phenotype. And it is dominant…

Q: In addition to the allelic pair determining pattern baldness in man (B,b), consider early baldness…

A: Introduction  Inheritance is referred to as the transfer of character from parents to offspring and…

Q: Charles has achondroplasia dwarfism (autosomal dominant) but his wife is normal. What is the…

A:

Q: If both parents carry one copy each of the mutation that causes Huntingtons , what are the odds that…

A: Huntington disease is the neurodegenerative disorder, it causes breakdown of nerve cells in the…

Q: What is the most likely mode of inheritance for the trait shown in the following pedigree? This…

A: This is an autosomal recessive trait.

Q: Acute murine leukemia virus (AMLV) causes leukemia in mice.This virus is easily passed from mother…

A: Extranuclear inheritance is also known as cytoplasmic inheritance. Cytoplasmic inheritance is…

Q: Male limited precocious puberty results from a rare, sex-limited autosomal allele (P) that is…

A: Dominant allele is one which is expressed over the other that is the other trait is completely…

Q: Cystic Fibrosis is an autosomal recessive disorder. A couple are both carriers of the recessive…

A: Cystic fibrosis is an inherited illness which affects the lungs and digestive system. The body…

Q: Vitiligo is a disorder in which melanocytes (cells that produce melanin pigment) are unable to…

A: In a purebred, the organism will breed true for the breed relevant traits. i.e., homozygous genotype…

Q: show effects of the allele under some circumstances (refer to the linked article and Mendelian…

A: Sickle cell allele refers to the abnormal allele of a person in which hemoglobin beta gene is…

Q: Along with the trait in the pedigree, individual IV-6 and the woman are also both heterozygous for…

A: A pedigree is a genetic representation of a family tree that shows how a trait or disease is passed…

Q: Tongue rolling is an autosomal dominant trait. What would be the phenotype of a person who is…

A: Those genes which are present in autosomal Chromosome are known as autosomal trait

Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.