Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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How to draw titration of amino acids ?what happen when ph increase from low to high?
1. what does it means when pka and ph are equal?
2. Did I calculate p1 correctly??
3. Does cysteine lose H in SH ?should it be positively charged or negatively charged after lose H and why??
Expert Solution
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Amino acids can act like an weak acid or base
Amino acids are biomolecules that have an amino group and a carboxyl group linked to the same carbon called alpha carbon. Other than the amino and carboxyl groups, amino acids have a side chain linked to the alpha carbon. Amino acids differ from each other in the side group that is linked to the alpha carbon.
The alpha-amino group and alpha-carboxyl groups are ionisable, the side group is ionisable in only some amino acids. When amino acids are dissolved in water, they can act either like an acid or like a base. This is why they are called dipolar ions or zwitterion.
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