How many milliliters of 1:100 epinephrine are needed for a 5 mg dose

30. A patient weighing 77 kg should receive a dose of 1.23 g of daratumumab (DARZALEX) in treating multiple myeloma. The drug is available in a 20-mL vial containing 400 mg of daratumumab. How many milliliters of this solution should be administered to provide the recommended dose?

A one-to-one protein (P)-ligand (L) complexation (P + L PL) has a dissociation equilibrium constant (Kd) value of 100 nM at 25°C, and the Kd remains the same at 37°C. 1) What is AS of binding at 25°C? Assume ACp of the binding is 0 over the temperature range. AS = 1.34E2 kJ/(mol*K) (note the unit!!) (sig. fig =3) 2) What is the concentration of the PL complex formed at equilibrium when you mix 0.20 uM (microM) of Protein and 1.0 uM of Ligand together at 37°C? PL at equilibrium = 8.1E-1 uM (note the unit!!) (sig. fig =2)

Jyan is 4 months pregnant and requires an IV infusion of magnesium sulfate heptahydrate at a rate of 5 g/hr for 5.3 hours. Magnesium Sulfate Concentrated Injection (2.465 g magnesium sulfate heptahydrate (MgSO4.7H₂O MWt = 246.5) in each 5 mL ampoule) is to be diluted with 5% w/v glucose solution to a concentration of 20 %w/v for infusion. What volume of 5% w/v glucose solution is required? (Whole number answer.)