3a) An 68 kg patient is to be given a 2.0 mg/kg body weight IV bolus dose of a newly developed antibiotic drug every 6 hours. Assume the half-life of the drug and its volume of distribution in the patient are 3.2 hours and 0.26 L/kg respectively. (a) Calculate the peak and trough plasma concentrations for the antibiotic after, one dose, two doses, four doses, and at steady state.

A 35 year old woman begins therapy with a drug( 50 mg twice daily) that has a volume distribution of 70L and an elimination half life of 2 days. According to first order kineticds, the average drug concentration will reach 75% of the average steady state blood concentration after how many days (A) 2 (B) 4 (C) 6 (D) 8 (E) 10

4) A 45-year old woman weighing 68 kg is admitted to hospital after a drug overdose. A toxic plasma concentration of 264 mg/mL is recorded on admission. After 35 hours, a plasma concentration of 8.25mg/ml is recorded. Given this information, calculate the half life for this drug.(Assume the distribution is complete and that the elimination is described by a first-order process.)unit- hours

A pharmacist is preparing a compounded oral suspension preparation using commercially available tablets as the source of the active pharmaceutical ingredient (API). The recipe is as follows:  "API" 0.8 mg/mL Structured suspension vehicle qs ad 240 mL Sig: 1 tsp PO BID PRN The tablets are available at a strength of 20 mg. Assume that when the the minimum number of tablets is used to prepare this compounded suspension, the crushed tablets take up 12.2 mL of volume.What volume of suspension structured vehicle will be needed to prepare this compounded oral solution?Round the answer to one decimal place.

mL b) Order of Ex.12: Calculate the following injectable dosages. a) Order of dosage: Lasix 40 mg intramuscularly. Supply: Lasix 10 mg/mL Give: dosage: Atropine 0.4 mg intramuscularly one hour pre-operatively. Supply: Atropine 1/150 grain/mL (or 0.0067 grain/mL) Give: dosage: Valium 7.5 mg intramuscularly stat. Supply: Valium 10. mg/mL Give: _mL Ex.13: Use the given table to determine the following. 23.2 g ice mL c) Order of cm3 = g table salt 25.0 cm3 mL 102.2 g gold = g/mL mg/L Ex.14: A cube of metal has a mass of 14.6 g and its sides 3 = m3 density of ethanol = are 12.3 mm. What is the identity of this metal? cm

49 A 1 litre infusion of sodium chloride 0.9% is being given at a rate of 28 drops/min (standard giving set). How long will the infusion run at the specified rate?

18. Esmolol 1.2 g in 500 mL D5W has been ordered at a rate of 100 mcg/kg/min for a client weighting 103.2 kg. Determine the following: a) dosage in mcg/min: b) rate in mL/hr c) Is the dosage administered to the client safe?

A pharmacist is preparing a compounded oral suspension preparation using commercially available tablets as the source of the active pharmaceutical ingredient (API). The recipe is as follows:  "API" 0.9 mg/mL Structured suspension vehicle qs ad 150 mL Sig: 2 tsp PO QD x14 day The tablets are available at a strength of 25 mg.  What is the minimum number of tablets needed to prepare this compounded suspension?  Round your answer up to the number of whole tablets to use.

全し67 9 PM Mon Apr 18 16) A patient weighing 99 lb is to receive Dextran 40, 1g per kilogram of body weight, intravenously over a 24-h period. The IV solution contains 10 g per 100 mL. (a) How many milliliters of the solution should be infused over 24 h? (b) Calculate the correct drop rate for a microdrop delivery system. Conne

Calculate the dose in Mg: What is the dose of a patient weighing 30 kg, if the dose is 10 mg/kg?