Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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How does the pyruvate dehydrogenase reaction control the citric acid cycle?
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- Which reaction in the citric acid cycle is most analogous to the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate? What kind of enzymebound intermediate is formed in both reactions?arrow_forwardHow many enzymes are involved in the citric acid cycle?arrow_forwardWhat would be the effect of the inhibition on other intermediates in the citric acid cycle?arrow_forward
- What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase and a-ketoglutarate dehydrogenase?arrow_forwardWhy is it that the carboxylate "ions" actually partake in the citric acid cycle ratherthan the carboxylic acid? Explain using an examplearrow_forwardHow does Pyruvate dehydrogenase contribute to metabolism?arrow_forward
- 1 2 points Order the following TCA cycle metabolites in the order they are produced in one turn of the citric acid cycle. Not all answers will be used. 2 1 4 3 TI Isocitrate Citrate Lactate Pyruvate Oxaloacetate Isocitrate Succinyl-CoA Aconitate 3-Phosphoglycerate -DOarrow_forwardWhat is the ATP yield from the oxidation of one molecule of nervonic acid?arrow_forwardHow many cycles of "citric acid cycle" are necessary to reveal the "C" that come from acetyl-CoA that take place in the first cycle known as "CO2"?arrow_forward
- Why is it reasonable for excess NADH to negatively regulate the citric acid cycle?arrow_forwardWhat are the initial reactants of the Citric Acid Cycle?arrow_forward1) An average middle-aged person weighing 90 kg (200 lb.) contains 15 % body fat stored in adipose tissue. a) Calculate the amount of energy stored as fat in this person in kilojoules, assuming that energy yield from fat is 37 kJ/g. b) If this same amount of energy were stored in hydrated glycogen rather than fat (hydrated glycogen has an energy yield of 6 kJ/g), how much would the person weight in kilograms and in pounds?arrow_forward
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