how does the change in the hormone feedback diagram explain the symptoms of feeling cold, weight gain and being tired from hypothyroidism?

Explain the concept of coordination in the context of endocrine system function. Differentiate exocrine from endocrine glands. Describe the roles of the hypothalamus, pituitary glands, target glands, and target organs. Enumerate the secretion of the hypothalamus and their functions. List the hormones secreted by the anterior and posteriors pituitary glands and their functions. Explain the hormonal secretion and their functions of the following: thyroid, parathyroid, adrenal (cortex and medulla), gonads (testis, ovaries), pancreas (beta and alpha cells), thymus, pineal glands. Describe the functions of hormones secreted by the following internal organs: heart, liver, kidney, stomach, small intestines, colon, and muscles Explain the concept of negative and positive feedback. Describe drugs that affect the endocrine system: thyroid replacement hormones, steroids, insulin. Give examples of nursing diagnosis that apply to issues of the endocrine system.

Which chemical category does GH belong to ? Which pathway of action does this hormone use ? is the GH receptor on the plasma membrane of Target cell or inside of the target cell? How do you know ?

Compare the long-loop negative feedback for the anterior pituitary hormones to the negative feedback loops for insulin and parathyroid hormone.