a) From the chemical structure above, write the amino acid sequence using both three-letter and one-letter abbreviations. Disregard chirality for this question. b) Indicate adjacent to the alpha-carbon of each residue whether it has an L- or D-configuration.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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a) From the chemical structure above, write the amino acid sequence using both three-letter and one-letter abbreviations. Disregard chirality for this question.

b) Indicate adjacent to the alpha-carbon of each residue whether it has an L- or D-configuration.

Question #1, continued:
(b) Somatostatin is a peptide hormone that produces a wide range of physiological effects, including inhibition
of the secretion of many hormones, such as the human growth hormone, thyroid stimulating hormone and gas-
trointestinal hormones. Given its physiological relevance, several analogs have been synthesized and are used
in the clinic, one of which is shown below.
HO
HO.
H
HN
NH₂
NH
OH
H
N.
NH
NH
ŃH₂
Transcribed Image Text:Question #1, continued: (b) Somatostatin is a peptide hormone that produces a wide range of physiological effects, including inhibition of the secretion of many hormones, such as the human growth hormone, thyroid stimulating hormone and gas- trointestinal hormones. Given its physiological relevance, several analogs have been synthesized and are used in the clinic, one of which is shown below. HO HO. H HN NH₂ NH OH H N. NH NH ŃH₂
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How do you identify the N vs C terminals?  For the first part of the question, do you then list the amino acids in order clockwise from N terminal to C terminal?

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