How different areoxyhemoglobin andhemoglobin? Where is itexpected to find a higherconcentration ofoxyhemoglobin, in peripheraltissues or in the lungs?

how does an increased PaCO2, respiratory acidosis, alter the delivery of oxygen to the tissues?

In high altitudes is itnecessary for the blood tohave more or lesshemoglobin?

Use the Hill Equation to determine the fractional saturation of hemoglobin in equilibrium with blood that has a partial pressure of 1.9 mmHg.

Suppose you visit the Dalai Lama in Dharamsala, India (elevation 1460 m),and you begin to ponder the “big questions,” such as “What is the fractionalsaturation of the Dalai Lama’s hemoglobin?”(a) Assuming the Dalai Lama’s hemoglobin has a Hill coefficient = 3.2,and a P50 = 31 mm Hg, calculate the change in fractional O2 saturationof his hemoglobin going from his lungs (where PO2 = 85 mm Hg) to hiscapillaries (where PO2 = 25 mm Hg).(b) Why do you suppose the Dalai Lama’s hemoglobin has a P50 higher thannormal (where “normal” = 27 mm Hg)?

What effect does hyperventilation have on blood pH and why? What simple measure can be used to correct the pH imbalance and how does it work? What effect would hyperventilation have on hemoglobin O2 saturation in a normal healthy individual? What effect would a PaO2 of 60 mmHg have on hemoglobin O2 saturation and why? (explain in terms of the O2-Hb dissociation curve)