
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Question

Transcribed Image Text:**Drug Delivery and Capsule Dissolution in Different Environments**
Hospital pharmacies and drug manufacturers have developed various gelatin capsules that can carry drugs which will only dissolve in specific acidic or basic media, *once they pass the mouth*. This control ensures that the drug is introduced precisely where needed in the human digestive tract. *We do not want things dissolving in the mouth or oral cavity.* Additionally, most drugs contain several different functional groups in their structure, often making them polyfunctional group molecules. With this context, please answer the following questions **in order**:
a) **Where will a capsule designed to dissolve in a basic environment dissolve, *after it is swallowed* with a glass of water?**
b) **What will happen (if anything) to a part of the drug molecule that is an amine salt, once the capsule dissolves? (Consider what will happen to it in the same location in the digestive tract where the capsule dissolves.)**
c) **What will happen (if anything) to a part of the drug molecule that is a carboxylic acid, once the capsule dissolves? (Consider what will happen to it in the same location in the digestive tract where the capsule dissolves.)**
d) **What will happen (if anything) to a part of the drug molecule that is an ether, once the capsule dissolves? (Consider what will happen to it in the same location in the digestive tract where the capsule dissolves.)**
e) **What will happen (if anything) to a part of the drug molecule that is an amine once the capsule dissolves? (Consider what will happen to it in the same location in the digestive tract where the capsule dissolves.)**
Expert Solution

This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution
Trending nowThis is a popular solution!
Step by stepSolved in 2 steps

Knowledge Booster
Similar questions
- Does the suggestion as to why methotrexate has such a high affinity CHANGE when told that crystallography determined that methotrexate binds to the protein with opposite orientation to folate? (two sentences should do it)arrow_forwardcan you help me with this question? the list at the bottom is for part a.arrow_forwardCan you please explain how to solve this problem?arrow_forward
- Consider the tripeptide serylalanylleucine. Part: 0 / 2 Part 1 of 2 Draw the structure of this tripeptide at physiological pH. Click and drag to start drawing a structure.arrow_forwardOne of your patients, a six-year-old girl who suffers from Sickle cell anemia, an inherited blood disorder in which red blood cells are abnormally shaped and fragile, leading to a short supply of red blood cells. These abnormal cells can also get stuck in small vessels, which prevent blood flow, leading to fatigue, pain and other severe complications. What molecules make up each single peptide? Deoxynucleotides (dNTPs) Nucleotides (NTPs) Amino acids DNA RNAarrow_forwardA polypeptide has: many peptide bonds O 4 peptide bonds O 2 peptide bonds O 3 peptide bonds O 1 peptide bondarrow_forward
arrow_back_ios
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education

Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON

Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax

Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,

Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company

Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.

Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education