Histologic examination of normal skin demonstrates small numbers of perivascular cells, with darklystained ovoid nuclei and granular cytoplasm on hematoxylin and eosin staining. The cellsdemonstrate metachromasia of the cytoplasm when stained with Giemsa stain. Which of thefollowing products would these cells be most likely to secrete?A. BradykininB. Complement factor 3aC. HistamineD. Interleukin 2E. Nitric oxide

The question is asking us to identify the type of cells described in the histologic examination of…

Answered: Histologic examination of normal skin…

An Illustrated Guide To Vet Med Term

4th Edition

ISBN:9781305465763

Author:ROMICH

Publisher:ROMICH

Chapter15: Feed And Protect Me

Section: Chapter Questions

Problem 2M

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A 60-year-old man presents with a skin lesion on his face, which has been increasing in size for the past 6 months. He has been a farmer by occupation. His past medical history is unremarkable. A biopsy of the lesion shows nests of atypical deeply basophilic cells extending from the overlying epidermis into the papillary dermis. The nests show peripheral palisading of the cells with haphazard arrangement in the center. Which of the following descriptions of gross appearance corelate to the microscopic findings seen in this lesion? Answers A - E A Pearly nodule with telangiectasia B Purple, pruritic, and polygonal lesion C Rough sandpaper consistency lesion D Round flat, coin like waxy plaque E Salmon colored plaque with silvery white scales O
Macropreparation No 3 Leukoplakia of the tongue Description of macropreparation: Diagnosis: Leukoplakia Micropreparation No 3 Leukoplakia of the tongue Staining: hematoxylin and eosin MAN Mark the corresponding elements in the picture: 1 - keratosis 2- multi-layered flat epithelium 3 - keranocytes 4- acanthosis 5- own plate 6-lymphomacrophagic infiltration of the underlying connective tissue Description: Name the outcomes of the process:
Explain the complement system under the following headlines: 1. Types 2. Activation 3. Complement fixation test
Complement activation is a cascade reaction, with each component sequentiallyacting on others, in a similar way to the blood-clotting system. Discuss the effectsthat occur when peptides are generated from the activation by either the classicalor the alternative pathway. This is an immunology question
Define plakophilin-2).
Explain the turn-over of the cells in epidermis and correlate it with the pathophysiology of the case of a patient with possible Psoriasis and Eczema: - 47 year old female with a a 3-week history of generalized, red, painful lesion in the limbs and trunk - overweight (BMI 26 kg/m2), has high blood pressure - Family history: Grandmother father side – skin cancer - a chain smoker (2 packs of cigarette per day) and an occasional alcoholic beverage drinker
Novobiocin susceptibility: Zone of inhibition or no zone of inhibition present: ______________ Novobiocin Susceptible or resistant: ______________________
A 3-year-old child has a history of serious infections and is currently hospitalized with meningitis. The doctor suspects that he may have a complement deficiency and orders testing. A buffer that chelates calcium was added to specimen. There was a decrease radial haemolysis on agarose plate a) Which complement pathway accounted for the result obtained and how will the result be reported in terms of hemolysis at 50 %? b) What is hydrodynamic focusing and why is it an important feature of an instrument.
Complement is an integral part of the innate immune response to bacteria . One of its mechanisms of action is to behave as an anaphylatoxin Describe the anaphylatoxic effects of complement identifying which components are activated.
A 4-year-old child has numerous small, white scales covering the extensor surfaces of the extremities, trunk, and face (shown in the image). The child's mother and grandmother have the same condition. Microscopic examination of the skin lesion shows hyperkeratosis and a thin stratum granulosum. Which of the following is the most likely pathogenesis of this disorder? Answers A - E A Antigen-induced release of mediators B Defective desquamation of keratinocytes C Dissolution of intercellular attachments D Excessive keratinocyte proliferation E UV light induced DNA damage O O O O CLOSE TOOLKIT
A 4-year-old child has numerous small, white scales covering the extensor surfaces of the extremities, trunk, and face (shown in the image). The child's mother and grandmother have the same condition. Microscopic examination of the skin lesion shows hyperkeratosis and a thin stratum granulosum. Which of the following is the most likely pathogenesis of this disorder? Answers A-E A Antigen- induced release of mediators B Defective desquamation of keratinocytes C Dissolution of intercellular attachments D Excessive keratinocyte proliferation E UV light induced DNA damage O O O Question #43 attachment CLOSE TOOLKIT
A research study investigates the synthesis of filaggrin-containing granules in skin biopsies from patients of atopic dermatitis. Which of the indicated layers is the site for these granules? Answers A - E AA B B C C D D EE O O O Question #44 attachment <-A B -C -D E

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