Phlebotomy Essentials
6th Edition
ISBN: 9781451194524
Author: Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher: JONES+BARTLETT PUBLISHERS, INC.
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An anti-inflammatory drug has a total body clearance (ClT) of 65 mL/min and is 70 % bioavailable after oral administration. If the drug is to be given orally every 8 hours, then what would be the maintenance dose (D) to achieve an average plasma concentration (Css,av) of 20 mcg/mL?
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