H3N. Amino acids are bonded together in a linear polymer to form peptides or proteins. A small peptide is shown below. Define the two ends of this peptide. A) I is the N terminus; II is the C terminus B) I is the C terminus; II is the N terminus C) I is the 5' terminus; II is the 3' terminus D) I is the 3' terminus; II is the 5' terminus

What is the function of the molecular chaperone? What would happen to the protein if molecular machine does not work?

Only answer please, no need to explain… Thank you for your time. i:  Modification of the 5 prime ends of eukaryotic mRNA is called? a) Capping b) Polyadenylation c) Splicing d) Transcription ii: Genetic Code is? a) The sequence of Nitrogenous Bases in mRNA that codes for a protein b) Is a Triplet Code      c) is Non-Overlapping      d) All of these iii. The process of formation of RNA is known as a) Replication          b) DNA repair         c) Translation           d) Transcription iv. Which of the following statement is NOT true regarding transcription/RNA synthesis? a) RNA synthesis occurs in the nucleus b) Unlike DNA synthesis, the only selective sequence of DNA is transcribed to RNA   c) RNA synthesis requires a short stretch of RNA primers d) DNA sequences, specific proteins, and small RNAs regulate RNA synthesis

4. You're working on a structure of a protein and its folding. You think that the interaction between Asp123 and Arg29 is important in determining the structure of the protein. a) What type of amino acid is Asp (acidic, basic, hydrophobic, or polar)? b) What type of amino acid is Arg (acidic, basic, hydrophobic, or polar)? c) What is the strongest interaction that can form between Asp123 and Arg29? You create a mutant Arg29> Lys d) What type of amino acid is Lys (acidic, basic, hydrophobic, or polar)? e) Would you expect this substitution mutation to cause major folding problems? Why or why not? You create mutant Arg29> Glu you discover that this mutant is unable to fold properly, so the protein is nonfunctional. f What type of amino acid is Glu (acidic, basic, hydrophobic, or polar)? g) How does this amino acid substitution cause the protein to fold incorrectly? You find another mutant that also as the same Arg29> Glu mutation. However, this mutant protein įs able to fold normally.…

Let’s suppose we have downloaded the structure of Hemoglobin from PDB. Now we want to retrieve the location of helices and loops in it. How can we do it? How can we depict a protein’s coordinate info in a modeling program? (Subject: Bioinformatics)

The term subunit can be used in a variety of ways. What is the difference between a protein subunit and a ribosomal subunit?

sugar and phosphate in a polynucleotide backbone are covalently linked by what? a) N-glucosidic bond  b) phosphodiester bond  c) peptide bond  d) beta strand e) alpha helix

In standard nomenclature, peptide sequences are read out in which direction? a) C to N b) 3’ to 5’ c) N to C d) 5’ to 3’

(A) Give the polypeptide translation of the RNA sequence below. 5’-AUGGAAAUCAAAGUCAACCUUGAGUUUAGA-3’ (B) Write the chemical structure of the polypeptide sequence you determined in part (a) (C) Given the chemical structure of the polypeptide sequence you have written in part (b), answer True or False for each of the 5 statements below. (1) At least one of the amino acids in the sequence can undergo phosphorylation (2) The sequence looks like it could form a β turn (3) The sequence looks like it could form a β strand with one surface facing the interior of the protein and the other surface exposed to water (4) At least one of the amino acids in the polypeptide sequence can undergo oxidation to form a disulfide bridge to another polypeptide (5) The sequence looks like it could form an α helix that would be part of a coiled coil structure within a protein

What general structural feature is shared by proteins that specifically form homodimers (but not homotrimers, homoteramers etc)? Only one answer is correct.     the surface consists of hydrophilic alpha-helix.   the surface is highly modified by post-translational modification.   the surface is permanently bound by chaperones.   the surface is unstructured.   the surface, or part of it, is self-complementary.