Grignard reactions are a convenient way to synthesize tertiary alcohols. Consider the following product, 4-Propyl-4-heptanol. Propose a synthesis of this compound that utilizes a Grignard reaction as the key transformation. You may use any compound or reagent that containing 4 or fewer carbon atoms. Please provide a literature reference for any step that is not common knowledge. OH

Following is the structural formula of the tranquilizer meparfynol (Oblivon). Propose a synthesis for this compound starting with acetylene and a ketone. (Notice the -yn- and -ol in the chemical name of this compound, indicating that it contains alkyne and hydroxyl functional groups.)

Wittig reactions with the following -chloroethers can be used for the synthesis of aldehydes and ketones. (a) Draw the structure of the triphenylphosphonium salt and Wittig reagent formed from each chloroether. (b) Draw the structural formula of the product formed by treating each Wittig reagent with cyclopentanone. Note that the functional group is an enol ether or, alternatively, a vinyl ether. (c) Draw the structural formula of the product formed on acid-catalyzed hydrolysis of each enol ether from part (b).

3 eq eq R 888 F4 V [Review Topics] [References] Draw structural formulas for an aldehyde or ketone and alkyl (or aryl) bromide that could be used in a Grignard synthesis of the alcohol shown. BE % 5 • You do not have to consider stereochemistry. . If there is more than one combination, draw only one. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. . Separate structures with + signs from the drop-down menu. 9 OH CH3CH₂CCH₂CH₂CH3 CH₂ CH ₂ C CH ₂ C CH3 T FS / JUL 1 9 B 6 ***** F6 Y MacBook Air H tv V 80 46924 0 0 • Sn [F & 7 SI N JA F7 U ** 8 DII FB I M ♫A ( 9 A 0▾ +▾ K DD FO O P V -O 085 9-81 L II... 10 人口 9 F10 - P A 90 S 000- SIF [F 8 F11 + ll = [ Previous F12 "1 ? Next> Save a 1 dele

2. Suggest the synthetic pathway to prepare the following compounds starting from 2- phenylethanol. More than one step may be required. a) Styrene b) Phenylacetaldehyde c) Phenylacetic acid

Hi, it's just one question but 3 subparts, and you are only allowed to answer up to 3 sub-parts please show the work clearly for all. Thank You

Synthesis of 3-Methylbutyl Ethanoate by an Acid Catalysed Esterification (FischerEsterification) & Purification by Simple Distillation Can you explain the details of what's going on this reaction please Specifics please i'll also leave a good review if you can help thank you

Devise a route to convert propene to propanone. Specify, in order, the reagents you would use. The reaction may require more than one step. If there is more than one feasible route, show only one. a NBS b H₂, Pd c H₂O, H₂SO4 d PCC e Br₂ in H₂O f K₂Cr₂O7, H₂SO4, H₂O, heat g Cl₂, heat or light h Cl2 i HCI j NaOH k OsO4/H₂O2 1. BH3 2. H₂O2, NaOH m SOCI2₂, pyridine I n Specify reagents using letters from the table, first reagent on the left. Example: ab The reagents are (in order of use): HBr o Br2,

Answer is two minor and one major product

Make a systematic process for the synthesis of the benzene derivative from benzene. Present all the needed reagent and reaction conditions and products. (Note the electron-donating or electron- withdrawing) NH2