Given the melting profile of a membrane bilayer consisting of (see attached diagrams) where R = palmitate (16:0), (see graph) where the x-axis is temperature in °C and the y-axis is the degree of fluidity (higher value means the membrane is more fluid), in what direction does the curve shift if: a. the palmitate were replaced with oleate (18:1) b. the palmitate were replaced with stearate (18:0) c. the choline head group is replaced with –OCH2 CH3

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Given the melting profile of a membrane bilayer consisting of
(see attached diagrams)
where R = palmitate (16:0),
(see graph)
where the x-axis is temperature in °C and
the y-axis is the degree of fluidity (higher
value means the membrane is more
fluid), in what direction does the curve
shift if:
a. the palmitate were replaced with oleate (18:1)
b. the palmitate were replaced with stearate (18:0)
c. the choline head group is replaced with –OCH2 CH3
Objective: Demonstrate some characteristics of different lipids and some techniques of
how we might be able to study them.
1. Given the melting profile of a membrane bilayer consisting of
H₂C
HC OCOR
H₂C OCOR
1
0.8
0.6
0.4
0.2
-CH₂CH₂N(CH3)3
where R = palmitate (16:0),
10
where the x-axis is temperature in °C and
the y-axis is the degree of fluidity (higher
value means the membrane is more
fluid), in what direction does the curve
shift if:
Transcribed Image Text:Objective: Demonstrate some characteristics of different lipids and some techniques of how we might be able to study them. 1. Given the melting profile of a membrane bilayer consisting of H₂C HC OCOR H₂C OCOR 1 0.8 0.6 0.4 0.2 -CH₂CH₂N(CH3)3 where R = palmitate (16:0), 10 where the x-axis is temperature in °C and the y-axis is the degree of fluidity (higher value means the membrane is more fluid), in what direction does the curve shift if:
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In 1c, the head groups are in the aqueous phase. Why would this affect the membrane fluidity?

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