For the following peptide chain WHD (Tryptophan-Histidine-Aspartic acid) :   pH = 8 Given pKa value for W : Alpha carboxy = 2.38  + Alpha Amino = 9.39 Given pKa value for H: Alpha carboxy = 1.82  + Alpha Amino = 9.17 Side chain = 6.04 Given pKa value for D : Alpha carboxy = 2.09  + Alpha Amino = 9.82 Side chain = 3.86 a. what is the charge of each amino acid residue

Q: how to determine net charge of amino acid, given pH and pKa values?

A: The formula of getting net charge is positive charge - negative charge . If pH and pKa  values are…

Q: Which amino acid listed in the pKa table may behave as a zwitterion at a pH of 7.0-7.4?

A: An amino acid acts as a zwitterion at its isoelectric point.

Q: Please identify the amino acid shown below: Arginine ΝΗ H₂N NH₂ OH Arginine If this amino acid was…

A:

Q: The isoelectric point of the tripeptide Gly-Ser-Ala occurs at a value below pH 7 C at pH 7 at a…

A: Here we have a tripeptide whose seq from the amino end to the COOH end is givenas Gly-Ser-Ala and we…

Q: What is the isoelectric point (pl) of arginine? Relevant amino acid structure is shown below: O…

A: Amino acid arginine structure.

Q: Consider a peptide: Glu-Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly-His If the pKa values for the…

A: If the pH of the solution is greater or equal to the pKa of side chain then the side chain will be…

Q: what are the lewis structures of these: H3PO4 SO42- Palmitic acid (in pH 7.4) Glycerol Water…

A: Lewis structure are drawn by making dots on the symbol of atom the number of dots are equal to their…

Q: The isoelectric point, pl, of the protein deoxyribonuclease I is 10.2, while that of clostripain is…

A: •Firstly understand about ISOELECTRIC POINT:-Isoelectric point is that value of pH where a molecule…

Q: Use these pka values to calculate the charge on the peptide below at pH 6. alpha COOH 2.0 side Chain…

A: T: Threonine, pKa: 9.0 S: Serine Y: Tyrosine, pKa: 10.0 M: Methionine C: Cysteine, pKa: 8.0 F:…

Q: What bonding/interaction(s) is possible between octane derivatives and peptides? O Cation-to-Anion O…

A:

Q: 8. The following proteins represent a wide range of molecular weights and isoelectric points. Mr is…

A:

Q: What is the principal species (PheH+, PheH and Phe) at the following pH for the amino acid,…

A: Given amino acid is phenylalanine. pka1 = 1.83 pka2 = 9.18 Pi is the isoelectronic point where amino…

Q: Estimate the pI of a dipeptide Cys-Asp assuming that the pKa values for αα-NH3+, αα-COOH, side chain…

A: The question is based on the concept of peptides. we have to identify the isoelectric point of given…

Q: T11.1. A student was provided with the following compounds: (i) N-acetyl-L-Aspartic acid (ii)…

A: In peptide synthesis, the condensation reaction between an amino acid and an amine involves the…

Q: Question 3 (. In this question the single letter abbreviations are used for amino acid residues, but…

A:

Q: Give the numbers of peptide bond present in given structure, structure is given at pH 10.5,  find…

A: The CO- NH bond is called peptide bond. A peptide bond connects two Amino acid units. Amino acid…

Q: 3. Draw the form of the amino acid that predominates at pH 11. G H₂N-CH- pka = 9.60 CH₂ pKa = 8.95 C…

A:

Q: Calculate isoelectric point (PI) of the peptide GSTSRASPRM. pKa N-terminus = 9.3; pKa R = 12.5; pKa…

A: The peptide is GSTSRASPRM.

Q: Given the following peptide RISAGDLEVK,  Determine the formal charge of peptide  a. pH=0.5 b.…

A:

Q: Consider a histidine residue within a protein. Based on the histidine side-chain pKa value of 6.0…

A: Histidine is a basic amino acid used to make up proteins which contain an amino group and a…

Q: Q1.Fill in positive, negative and neutral The isoelectric point, pl, of two amino acids is shown…

A:

Q: Fill in the Blanks q OH Type your answers in all of the blanks and submit X, X' Ω· For the following…

A: The characteristic pH at which the net electric charge is zero is called the isoelectric point (pI).…

Q: 14. ¿Qué porcentaje de glicinamida, ⒸH₂NCH,CONH, (pK 8.20) no está protonado a a) pH = 7.5, b) pH =…

A: Given in following question

Q: Aspartic acid has the following pKa values: Alpha carboxyl group =2.1 , side chain carboxylgroup =…

A: The question is based on the concept of amino acids. We need to draw the structure of aspartic acid…

Q: This is a three-part question about a tripeptide. Answer all three sub-questions. The pKR of side…

A:

Q: C. Amino Acids and Peptides. Consider the following amino acids: H₂N-CH-1-OH CH₂ H₂N-CH-C-OH CH₂…

A:

Q: Show the condensation reactions that result in the formation of the tetrapeptide Asp-Gly-Ser- Gln.…

A: Given: Asp, Gly, Ser, GIn To determine: 1) The condensation reactions that result in the formation…

Q: The isoelectric point of a polypeptide or protein is equal to the pH at which the overall charge is…

A: We know if the pH is greater than pka, then deprotonation occurs and it exists in deprotonated form.…

Q: The pKa values of an amino acid are the following: pK1 = 2.18;  pK2 = 8.95;  pK3 = 10.53, what is…

A: Tha pKa values indicates ;  pK1 = 2.18 ( this is the pKa of acidic group)  pK2 and pK3 are the pKa…

Q: Complete the following reaction: Naz-peptide -Peptide (A) CH والی CH3 2P3 NA₂ CH H NH₂ V=0

A: SNAr reactionHydrolysis

Q: Calculate the isoelectric pH of this peptide: His-Tyr

A: Here we are required to find the isoelectric point pH of the peptide.

Q: Glutamic acid (Glutamate) has an R group that has the following pKa values 2.19, 4.25 and 9.6. Draw…

A: "Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: Consider the peptide below, and indicate which of the following would accurately select all that…

A: The given tripeptide structure is shown below.The given options are shown belowWe have to select all…

Q: Charge of dipeptides 2c On paper draw a dipeptide, clearly showing the peptide bond joining the two…

A:

Q: Calculate the isoelectric point for below amino acid. asparagine: pKa (COOH) = 2.02; pKa (α-NH3+) =…

A: Given: pKa (COOH) = pKa1 = 2.02 pKa (α-NH3+) = pKa2 = 8.80 Isoelectric point (pI) is simply equal to…

Q: (p) Trace the hemiacetal in the following monosaccharide: CH₂OH O CH₂OH OH OH OH (q) Identify the…

A:

Q: Calculating the pl for an amino acid without an ionizable side chain is straightforward. Simply the…

A: The isoelectric point (pI) of an amino acid is the pH at which a particular molecule carries no net…

Q: Draw structure of the following amino  acids in the charged form that predominates at ph 10:…

A:

Q: At what pH would you carry out an electrophoresis to separate the amino acids in each mixture? Q)…

A: The isoelectric points of the amino acid mixture Glu, Gin, Asp are 3.08, 5.65, and 2.98…

Q: Identify the outlined functional groups present in the amino acid and peptide compounds. + H3N-…

A:

Q: The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COOH…

A: Molarity of Histidine solution = 0.11 MThe volume of Histidine solution taken = 80 mLpH of Histidine…

Q: The amino acid Asp is triprotic with pK₁ = 1.88, pK2 = 9.60, and pK3 = 3.65. What is the charge of…

A:

Q: What is the net charge of the tripeptide His-Asp-Tyr at pH 12? The table below gives the pKa values…

A: The objective of this question is to find the net charge of tripeptide His-Asp-Tyr.

Q: Which amino acid must have been used to form the ring highlighted in this structure? A) R B) S C) T…

A: The given structure is shown below

Spectroanalytical Methods

Spectroanalytical methods measure the wavelength and intensity of radiations that are either emitted or absorbed by a molecular or atomic species. These methods are useful for evaluating the electronic or atomic arrangement of the molecules of a given analyte.