Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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Following is a retrosynthetic analysis for the anthelmintic (against worms)
diethylcarbamazine.
N.
`NET2
N.
OEt
Me
Me
Diethylcarbamazine
(A)
(2)
OH
MENH,
CI
OEt
Me
OH
Me
Methylamine
Ethylene
(C)
(В)
Ethyl
oxide
chloroformate
Diethylcarbamazine is used chiefly against nematodes, small cylindrical or slender
threadlike worms such as the common roundworm, which are parasitic in animals and
plants. Given this retrosynthetic analysis, propose a synthesis of diethylcarbamazine
from the three named starting materials.
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Transcribed Image Text:Following is a retrosynthetic analysis for the anthelmintic (against worms) diethylcarbamazine. N. `NET2 N. OEt Me Me Diethylcarbamazine (A) (2) OH MENH, CI OEt Me OH Me Methylamine Ethylene (C) (В) Ethyl oxide chloroformate Diethylcarbamazine is used chiefly against nematodes, small cylindrical or slender threadlike worms such as the common roundworm, which are parasitic in animals and plants. Given this retrosynthetic analysis, propose a synthesis of diethylcarbamazine from the three named starting materials.
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