First, identify the STRONGEST NON COVALENT interaction that could occur between each group present on a substrate molecule and a functional group found in the active site in an enzyme? Next, for each functional group in this exercise, pick an amino acid whose side chain (three letter abbreviations might be in the active site of an enzyme and form the type of interaction you identified (Note: not all 20 side chains are possible answers). Carefully examine the protonation state and charge of the functional groups provided when you consider your answers. Substrate FG Type of interaction a. coo Đ NHI C-SH d. C6H6 lonic H-bond Show Transcribed Text ĐỊNH dipole-dipole London interaction Leu Asn G-SH protonated Lys deprotonated Glu First, identity the STRONGEST NON COVALENT interaction that could occur between each group present on a substrate molecule and a functional group found in the active site in an ennyme? Next, for each functional group in this exercise, pick an amino acid whose side chain three letter abbreviation) might be in the active site of an ennyme and form the type of interaction you identified (Note: not all 20 side chains are possible answers). Carefully examine the protonation state and charge of the functional groups provided when you consider your answers. Substrate FG Type of Interaction a. Coo d. C6H6 Amino acid sidechain Amino acid sidechain lanic H-bond dipole-dpale London interaction Leu Asn protonated Lys deprotonated Glu

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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First, identify the STRONGEST NON-COVALENT interaction that could occur between each group present on a substrate molecule and a functional group found in the active site
in an enzyme? Next, for each functional group in this exercise, pick an amino acid whose side chain @three letter abbreviation might be in the active site of an enzyme and form
the type of interaction you identified (Note: not all 20 side chains are possible answers). Carefully examine the protonation state and charge of the functional groups provided
when you consider your answers.
Type of interaction
Substrate FG
a. COO
o Nha
C.-SH
d. C6H6
ionic
H-bond
dipole-dipole
London interaction
Leu
Asn
protonated Lys
deprotonated Glu
Show Transcribed Text
d. C6H6
First, identity the STRONGEST NON COVALENT interaction that could occur between each group present on a substrate molecule and a functional group found in the active site
in an enzyme? Next, for each functional group in this exercise, pick an amino acid whose side chain three letter abbreviation) might be in the active site of an enzyme and form
the type of interaction you identified (Note: not all 20 side chains are possible answers). Carefully examine the protonation state and charge of the functional groups provided
when you consider your answers.
Substrate FG Type of Interaction
a. coo
B NHI
C-SH
Amino acid sidechain
Amino acid sidechain
lonic
H-bond
dipole-dipole
London interaction.
Leu
Aso
protonated Lys
deprotonated Glu
Transcribed Image Text:First, identify the STRONGEST NON-COVALENT interaction that could occur between each group present on a substrate molecule and a functional group found in the active site in an enzyme? Next, for each functional group in this exercise, pick an amino acid whose side chain @three letter abbreviation might be in the active site of an enzyme and form the type of interaction you identified (Note: not all 20 side chains are possible answers). Carefully examine the protonation state and charge of the functional groups provided when you consider your answers. Type of interaction Substrate FG a. COO o Nha C.-SH d. C6H6 ionic H-bond dipole-dipole London interaction Leu Asn protonated Lys deprotonated Glu Show Transcribed Text d. C6H6 First, identity the STRONGEST NON COVALENT interaction that could occur between each group present on a substrate molecule and a functional group found in the active site in an enzyme? Next, for each functional group in this exercise, pick an amino acid whose side chain three letter abbreviation) might be in the active site of an enzyme and form the type of interaction you identified (Note: not all 20 side chains are possible answers). Carefully examine the protonation state and charge of the functional groups provided when you consider your answers. Substrate FG Type of Interaction a. coo B NHI C-SH Amino acid sidechain Amino acid sidechain lonic H-bond dipole-dipole London interaction. Leu Aso protonated Lys deprotonated Glu
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