Find and determine the R or S configura- tion for all chiral carbons in Geldanamycin, an antibiotic. You must be clear on which carbon atoms you are assigning the con- figurations to; draw arrows to the chiral carbon if you have to. Hint: There are six chiral carbons in this molecule. Calculate the total number of stereoisomers for Gel- danamycin. The formula for doing so is 2", where n is the number of stereocenters. CH30. H3C CH3O OH NH CH3 CH 30 CH3 NH₂

Chemistry: Matter and Change
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ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
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Chapter23: The Chemistry Of Life
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Problem 62A
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Find and determine the R or S configura-
tion for all chiral carbons in Geldanamycin,
an antibiotic. You must be clear on which
carbon atoms you are assigning the con-
figurations to; draw arrows to the chiral
carbon if you have to. Hint: There are six
chiral carbons in this molecule. Calculate
the total number of stereoisomers for Gel-
danamycin. The formula for doing so is 2",
where n is the number of stereocenters.
CH 30.
H3C
CH3O
OH
NH
CH3
CH 30
CH3
NH₂
Transcribed Image Text:Find and determine the R or S configura- tion for all chiral carbons in Geldanamycin, an antibiotic. You must be clear on which carbon atoms you are assigning the con- figurations to; draw arrows to the chiral carbon if you have to. Hint: There are six chiral carbons in this molecule. Calculate the total number of stereoisomers for Gel- danamycin. The formula for doing so is 2", where n is the number of stereocenters. CH 30. H3C CH3O OH NH CH3 CH 30 CH3 NH₂
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