Q: Summarize the impact of age-related physiologic changes on the pharmacokinetic aspects of drug…
A: Health refers to the well-being of a person. Disease or disorder refers to improper functioning of…
Q: What do you know about pharmacodynamic drug development? Explain briefly
A: Pharmacodynamic drug development deals with biochemical and physiological effects of drug and…
Q: Explain the role of LC50 in ensuring the safety of a drug candidate? Explain at your own words
A: Drugs are defined as the type of chemical substances where they produce changes in the physiology or…
Q: Define therapeutic index and explain its importance.
A: Therapeutic Index is also known as Therapeutic Ratio. It is a quantitative measurement of the…
Q: Define about Optimizing Drug Responses ?
A: Optimization is the process of making the best use of something. Drug optimization in health care is…
Q: Describe the different types of trials a new drug must undergo before it is “ready for market.”
A: A drug is a chemical substance that produces a biological effect. When the drug is taken by…
Q: Review some of the ways to reduce levels of drug resistance.
A: Microbial resistance to a drug occurs when there are spontaneous mutations in critical chromosomal…
Q: Describe the significance of the use of pharmacokinetic parameters in case to calculate appropriate…
A: Pharmacokinetics is the study of a drug that is administered to a living Organism which describes…
Q: Define therapeutic effect
A: Therapeutic effect can be best described as a primary effect that is intended and is the reason we…
Q: In the dose response curve below, Drug B has [ Select ] * potency and [ Select ] efficacy as Drug A
A: Efficacy and potency are two characteristic features of a drug, which shows how effective and potent…
Q: Discuss the effects of glass packaging materials on pharmaceutical dosage form? Discuss at your own…
A: Packaging refers to the process of wrapping or safeguarding products in preparation for delivery,…
Q: Explain the phenomenon of drug resistance from the standpoint ofmicrobial genetics (include a…
A: Microbes such as bacteria, fungi, protozoa, and viruses, etc, provide a relatively simple system for…
Q: ase give point on
A: Drugs are any substances when taken into the body bring out psychological and physiological changes…
Q: Explain the benefit of narrow spectrum over broadspectrum drugs
A: A broad spectrum drug is one that is effective against a wide range of microbial organisms to treat…
Q: Define the process of H1-Antihistamine drug discovery?
A: Antihistamines -- Antihistamine are the drugs typically used against the allergies . Medically the…
Q: Distinguish the clinical phases of drug development
A: Drug development is the process of bringing a new drug molecule into clinical practice. This is…
Q: Explain the term low therapeutic index.
A: Therapeutic index is the window of dosage of that drug in which it is therapeutically effective,…
Q: Describe the influence of protein binding on drug bioavailability
A: Protein binding is the extent to which drugs can bind to proteins in the blood or tissues. The…
Q: Explain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.)…
A: A drug is any substance that can affect psychology or physiology when taken into the body. It is…
Q: Describe the five basic mechanisms of drug resistance.
A: Antibiotics are the drugs which are used to kill the pathogenic bacteria. Penicillin is the first…
Q: Briefly explain the therapeutic drug monitoring of Warfarin? Please explain at your own words
A: Warfarin is called Coumadin and it acts as an anticoagulant. It is used to treat embolism,…
Q: List all the possible modes of entry of the drug to the target cell membranes.
A: There are different ways of entry of drugs to the target cell membrane. The most important ones are…
Q: Explain mechanisms of drug toxicity? How various strategies are used to treat the drug toxicity and…
A: Drug toxicity can be outlined as the toxicity which occurs because of ingesting more drugs that are…
Q: Explain the concept of selective toxicity in terms ofantimicrobial therapy.
A: The antimicrobial drug helps in eliminating the pathogenic microorganism from the host body cells…
Q: Describe the Mechanisms of Drug Resistance with an example.
A: Resistance is improvement of the capacity to withstand the beforehand dangerous impact of a drug by…
Q: Suggest strategies to overcome drug resistance
A: Answer- Drug resistance is the situation in which the effectiveness of a drug or a medicine is…
Q: Discuss some of the ways for reducing levels of drug resistance
A: Introduction: Antimicrobials are chemicals that kill bacteria or restrict their growth.…
Q: What is meant by a therapeutic window of a drug? b. Is it beneficial for a drug to have a wide or…
A: Therapeutic window refers to the period when the drug imparts it's therapeutic drugs on the body and…
Q: Explain the term first-pass eject or hepatic metabolism of the drug. What effect does first-pass…
A: Introduction:- Drugs are the form or a type of medicine which are used to treat different types of…
Q: Describe the factors that affect both drug absorption and bioavailability.
A: Drug absorption : The most important principle in pharmacokinetics theory is drug absorption. The…
Q: Describe some Specific Drugs and Their Metabolic Targets. Give some uses.
A: Drug metabolism is a term used to describe the biotransformation of drugs in the body for easy…
Q: Define about Sulfa Drugs ?
A: Antibiotics are considered chemical compounds, which are helping to prevent bacterial infections.
Q: What is the process that leads to drug tolerance?
A: The effect of the drug lessens with repeated exposure. Bigger doses drug is required to bring…
Q: Draw and explain the conceptual pathway of mechanism, transport and excretion of drugs. (subject:…
A: In pharmacology, drugs are defined as chemical substances or compounds used as medicines, which…
Q: Explain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.)…
A: In the development of a new drug it is very important make sure about the safety profile of the…
Q: Explain what is meant by a drug’s spectrum and how narrow- andbroad-spectrum drugs differ.
A: Spectrum simply means the range. The spectrum of a drug means the range of microorganisms it can…
Q: Explain how drugs may interact with nucleic acids as a drug target, and outline how a medicinal…
A: Drugs are used to treat a disease. The disease is caused when there is a deviation from the normal.…
Q: Briefly discuss reasons why metabolism is a major cause of variations in drug response and or…
A: Drug definition Medication or medicine that causes physiological changes when consumed. Factors…
Q: The Enteral route of drug Administration is the most convenient route of dministration of drugs.…
A: The route of the drug is also identified by the site of the prescription of the drug. It would be…
Q: Define the concept of drug bioavailability and briefly explain how it is experimentally determined.…
A: bio-availability of a drug is the indicator or measure to check how much the administered dosage of…
Q: Explain the role of toxicological parameters LOAEL in ensuring the safety of a drug candidate.…
A: In the development of a new drug, it is very important make sure about the safety profile of the…
Q: What do you know about pharmacodynamic and pharmacokinetic drug development? Explain briefly
A: Drug research:It encompasses many diverse disciplines that are united for a common goal, the…
Explain the uses of the minimum inhibitory concentration and the
therapeutic index in drug selection.
Step by step
Solved in 3 steps
- What are the various structures of drug regulation? Please answer at your own easy words. Answer should be to the point.Define therapeutic index and explain its importance. Identify the classification of drug metabolism and specific type of reaction involved in each drugsample. Identify the enzyme involved in each reaction.
- Identify the classification of drug metabolism and specific type of reaction involved in each drugsample. Identify the enzyme involved in each reaction.Describe the influence of protein binding on drug bioavailabilityExplain the role of LC50 in ensuring the safety of a drug candidate? Explain at your own words
- Briefly explain this statement "Preformulation studies help to find the drug performance and the development of a dosage form"-explain this with different drug properties and example? Please answer at your own easy words.Explain the relationship between the minimum inhibitory concentrationand the therapeutic index. What is optimum for each?Enumerate the different sources of drug. Provide example for each source. Discuss the advantages and disadvantages of each source.
- Show the relationship of Drug therapy processes to the different branches of Pharmacology.How we can identify the drug-drug interaction and how can it be prevented? explainIdentify the binding interactions that might be possible for the drug reported below. Rank these interactions by increasing energy.