Explain the difference between slow and fast chemical transmission. Fig. 8.23

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
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  1. Explain the difference between slow and fast chemical transmission. Fig. 8.23

 

FIG. 8.23 ESSENTIALS Fast and slow postsynaptic responses
Presynaptic axon
terminal
Fast responses are mediated
by ion channels.
Slow responses are mediated by
G protein-coupled receptors.
Neurotransmitters create
Neuromodulators create
rapid, short-acting
fast synaptic potentials.
slow synaptic potentials
and long-term effects.
Neurocrine
Chemically
gated ion channel
G protein-coupled
receptor
R
Inactive
Postsynaptic
cell
pathway
Alters open
state of
ion channels
Activated second
messenger pathway
Modifies existing
proteins or regulates
synthesis of new
proteins
lon channels open
lon channels close
More K*
More
Nat in
Less
Na* in
Less K+
out
out or
CIF in
IPSP =
Coordinated
intracellular
EPSP =
excitatory
depolarization
inhibitory
hyperpolarization
EPSP =
excitatory
depolarization
response
Transcribed Image Text:FIG. 8.23 ESSENTIALS Fast and slow postsynaptic responses Presynaptic axon terminal Fast responses are mediated by ion channels. Slow responses are mediated by G protein-coupled receptors. Neurotransmitters create Neuromodulators create rapid, short-acting fast synaptic potentials. slow synaptic potentials and long-term effects. Neurocrine Chemically gated ion channel G protein-coupled receptor R Inactive Postsynaptic cell pathway Alters open state of ion channels Activated second messenger pathway Modifies existing proteins or regulates synthesis of new proteins lon channels open lon channels close More K* More Nat in Less Na* in Less K+ out out or CIF in IPSP = Coordinated intracellular EPSP = excitatory depolarization inhibitory hyperpolarization EPSP = excitatory depolarization response
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