Explain how the class of antibody that normally exists as a pentamer changes its conformation to reveal binding sites for C1 upon binding antigen. Why is it important that the C1-binding sites are hidden until the antibody binds antigen?

Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter45: The Immune System: Internal Defense
Section45.5: Antibody-mediated Immunity
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Explain how the class of antibody that normally exists as a pentamer changes its conformation to reveal binding
sites for C1 upon binding antigen. Why is it important that the C1-binding sites are hidden until the antibody
binds antigen?
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