Epilepsy is often treated with a combination of drugs such as carbamazepine and phenytoin (polytherapy). CYP3A4 is induced by phenytoin and carbamazepine. Carbamzeipine is cleared by CYP3A4, but phenytoin is not cleared by CYP3A4. What problems might you expect if (a) carbamazepine is removed or (b) phenytoin is removed from this two-drug regimen.

Epilepsy is often treated with a combination of drugs such as carbamazepine and phenytoin (polytherapy). CYP3A4 is induced by phenytoin and carbamazepine. Carbamzeipine is cleared by CYP3A4, but phenytoin is not cleared by CYP3A4. What problems might you expect if (a) carbamazepine is removed or (b) phenytoin is removed from this two-drug regimen.

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter10: Reconstitution Of Powdered Drugs

Section: Chapter Questions

Problem 4.7P

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