Discuss the role of autoantibodies in three named autoimmune diseases, then discuss how four named monoclonal antibody therapies (biologics) have been used to treat patients with autoimmunity. Use the aid of many diagrams.

Describe three examples of how antibodies are used as reagents in cell biology and molecular biology.

Identify which of the following statements regarding naive T cells is incorrect. a. Naive T cells have the capacity to survive for many years as nondividing circulating cells in the absence of specific antigen. b. Naive T cells express LFA-1 molecules that change their conformation after encountering a specific peptide:MHC complex. c. Naive T cells exit from lymph nodes using the same route as effector T cells. d. Naive T cells express ICAM-3, which binds to DC-SIGN on dendritic cells with high affinity. e. Naive T cells express high levels of S1P receptors on their surface.

Herd immunity means that the entire population (not just those who are vaccinated) are protected from a disease.  What is one way that herd immunity protects an unvaccinated person (such as an infant who is too young to be vaccinated or a person who is immunocompromised)?