Din Diarin wants to methylate the diphenol shown below using methyl bromide. Thereaction is a simple nucleophilic substitution, and requires both phenol groups to bedeprotonated by a base so that the resulting phenoxide may attack the alkyl halide andform a C-O bond.HOBase+BrDMF/H20ОНNH2Potentialbases1) КОН2)3) K2CO34) CSOH5)a) Which of the potential base(s) would likely be an acceptable choice to ensure anefficient reaction under the current reaction conditions? Briefly explain your answer.

The explanation is given below-

Answered: Din Diarin wants to methylate the…

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter19: Enolate Anions And Enamines

Section: Chapter Questions

Problem 19.57P

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