Describe the structure and functions of hyaluronic acidand proteoglycan aggregates.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Describe the structure and functions of hyaluronic acid
and proteoglycan aggregates.

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Step 1

The extracellular matrix (ECM) can be described as an extensive network of multidomain macromolecules that organizes the cell and tissue. The elements of the ECM tie together to form a strong structure. It is found in both animal and plant cells.

Step 2
  • Hyaluronic acid consists of disaccharide repeating unit such as glucuronic acid and N-acetyl glucuronic acid of the extracellular matrix that act as connective tissue. It is involved in cell and tissue hydrodynamics, ion exchange, and the transport of various compounds. HA helps preserve natural water balance, tissue hydration, moisture recovery, permeability, and circulatory system in various tissues and organs.
  • Proteoglycan aggregate is a structural component of cartilage's extracellular matrix (LP) composed of Aggrecan, hyaluronan (HA), and attachment protein. The aggregates give cartilage a distinctive gel-like texture and resistance to water absorption, making it more resistant to deformation.
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