Demonstrate the steps involved in transcription of fibroblast cells.

Q: Define enhanceosome.

A: The enhanceosome can be defined as:

Q: Explain Phenotypes of mutations in genes encoding transcription factors.

A: Some genetic disorders caused by mutation in genes encoding components of the transcriptional…

Q: (a) Delineate an apoptosis initiated sequence of post-PDI activity in detail. How can tosis…

A:

Q: Discuss the possible effects of a defective tubulin gene in a cell

A: Answer:  TUBULIN = This is a type of protein that combines and forms in to long chains and filaments…

Q: Discuss the role of chromatin proteins in regulating gene expression. How does the three-dimensional…

A: Chromatin is a part of the nucleus of the eukaryotic cell. This highly organized complex of DNA and…

Q: What are the normal functions of the BRCA1 tumor suppressor gene?

A: The BRCA1 gene codes for the protein that causes breast cancer type 1. BRCA1 is a human tumour…

Q: Distinguish between general and regulatory transcription factors.

A: The transcription factors are protein that controls the transcription rate of genetic information…

Q: 14)How does a compound that inhibits the GTPase activity of ras affect cell responses to growth…

A: Ras's GTPase activity is essential for controlling how cells react to growth stimuli. Ras is a tiny…

Q: Describe the specific molecular events that occur within a cell in response to growth factors…

A: Cellular response:                 Signals and receptors pile in many varieties and binding can…

Q: Describe in detail the relevance of apoptosis to cancer therapy

A: Apoptosis or programmed cell death  It is a highly regulated process that allows a cell to self…

Q: Define Suppressor Mutations.

A: Suppressor mutations are helpful for distinguishing new genetic sites that have an effect on a…

Q: Diferentiate between embryonic and adult stem cells.

A: Cell is the basic structural and functional unit of all living organisms. Cells are classified into…

Q: List the Pol II general transcription factors.

A: Transcription factors is a protein that controls the rate of transcription of gentic information…

Q: Define about Several types of cellular stress events bring about rapidincreases in the nuclear…

A: The p53 is also known as the guardian of the genome. It is a tumor suppressor gene. The function of…

Q: Explain how mutations in oncogenes and in tumor suppressorgenes cause cancer.

A: Cancer is a group of diseases that involves abnormal growth of the cell. These cells have the…

Q: A mutated form of protein p5x is found in patients with squamous cell carcinoma. In vitro studies…

A: A gene that produces a protein that is essential for regulating cell division and death and is…

Q: Explain why IC3 is able to stop cancerous cells from dividing ?

A: Tumor-suppressor proteins are those proteins that normally act to stop abnormal cell growth. But…

Q: Mutations in the RB gene are often associated with cancer. Explain how a mutation that results in a…

A: The cell cycle is the series of stages that allow the cell to pass from one cell division to…

Q: Describe the ATM-p53 repair pathway in normal cells and cancerous cells

A: Apoptosis is a genetically controlled mechanism of cell death, which is important for the…

Q: Please explain the role of gene expression in the process of a stem cell differentiating into a…

A: Gene expression is the process of central dogma where protein is formed from DNA. Stem cells have…

Q: Describe the main events in the transcription of geneticinformation from DNA into mRNA?

A: Introduction  A genome is consists of transcriptionally active genes. These genes form mRNA as they…

Q: Explain how iRNA works to down-regulate gene expression.

A: A mutation is a permanent change in the DNA of a cell such that the sequence deviates from what is…

Q: once transcription is complete gene expression is controlled by..........?!

A: In eukaryotic cells, after the transcription, the RNA needs to be modified or Processed into a finer…

Q: Explain why mutations can give rise to neoplasms

A: The genetic alteration results in the advantage in growth of the cell. The 3 genetic change…

Q: Explain circadian rhythms in terms of gene expression.

A: " ANSWER  Circadian rhythms Are powered with the aid of an intrinsic timing machine this is…

Q: Describe the regulation of gene expression.

A: The gene expression the process in which the genetic information present in the DNA (gene) is copied…

Q: Explain about general transcription factors (GTFs) ?

A: In cells, the genetic information is stored in DNA. The DNA has segments that code for specific…

Q: Explain the Role of telomere in regards to cancer

A: Telomeres gradually shorten with each cell division, resulting in less protection for the…

Q: Under what circumstances is cancer considered to have ahereditary component?

A: The abnormal growth of cells that leads to deleterious effects in the body is referred to as cancer.…

Q: What is the importance of the EMT during metastasis?

A: EMT  is an evolutionary conserved developmental program which is implicated in carcinogenesis.

Q: How did the intrinsic pathway ofapoptosis evolve, and what is theadvantage of having…

A: When a cell becomes dead this is known as Apoptosis. In Apoptosis the material present in the cell…

Q: explain the role of the two CKI families, such as INK4 and CIP/KIP in regulating adult stem cell…

A: Adult stem cell quiescence refers to a state of temporary and reversible cell cycle arrest that…

Q: Mutations in p53 are commonly associated with malignant tumor formation. Do deleterious mutations in…

A: Mutations are the phenomenon in which certain nitrogenous bases are removed or added spontaneously…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.