Define platelet activation and list the class. types of molecules released from granules and Describe how PGI2 and ADPase regulate platelet function

Describe the changes in clotting and bleeding balance during disseminated intravascular coagulation (DIC). Describe the most important blood coagulation tests used to monitor the patients receiving heparin and warfarin. Distinguish between immediate and delayed hypersensitivity. What drugs are used to treat immediate hypersensitivity and how do these drug work? Why don’t these compounds work in treating delayed hypersensitivity?

Rho activation is preceded by association of a Rho regulator to regions of the plasma membrane just “above” where the contractile ring will form. Which regulator (Rho GAP or Rho GEF) would you predict would be localized to this region of the cell? Briefly explain your reasoning.

Describe the location, precursors and factors related to maturation and selection of B lymphocytes and T lymphocytes.