Define ‘gene’. What is an allele and loss-of-function alleles? What do these alleles tell us about normal gene function?

Q: What is the proper route for gene delivery in different kinds of disorders?

A: Gene therapy is a promising method for correcting host pathology by the manipulation of DNA…

Q: In a first attempt to describe the relationship between genes and phenotypes, Beadle and Tatum in…

A: One gene-one enzyme hypothesis was discovered in the early 1940s that each gene controls the…

Q: Mutant C has had the first 5 base pairs deleted (position 1-5). Does this mutation change the…

A: Translation is the process which is responsible for synthesis of protein from the mRNA.

Q: Discuss the similarities and differences of phenotypic variations that are caused by epigenetic gene…

A: Genetics is a branch of science that deals in the study of genes, heredity, and genetic variation of…

Q: Why are diseases due to microsatellite amplification, even though they have a monogenic pattern of…

A: The classical inheritance is the type of inheritance pattern in which mendelian laws are followed…

Q: Give at least 3 examples each of internal and external factors that affect penetrance and…

A: Penetrance is a term used to define whether or not a genotype has a clinical expression in a person.…

Q: There are some genes where the phenotype of an individual is dependent on the mother's genotype.…

A: Maternal genes are those genes whose products, RNA or protein, are produced or deposited in the…

Q: What is effect of turning on and off of genes? How do we measure gene expression? What is gene…

A: Answer1) The effect of turning a gene on and off is observed on its expression and ultimately on the…

Q: n and Give examples of mutations that can have global effects on gene expression.

A: Mutation is defined as any change or alternation in the sequences of DNA or, in the case of…

Q: Explain how environmental factors can modify gene expression?

A: This is true that environmental factors can modify the gene expression, these environmental…

Q: Explain how the environment may influence genetic expression.

A: The expression of genes in a living being can be influenced by the climate, remembering the outer…

Q: B. Briefly describe how can RNA seq be used to quantify differential gene expression between two…

A: It is attainable by performing RNA-Seq with spike-ins, samples of ribonucleic acid at identified…

Q: Explain

A: The process by which information encoded in a gene is used to control the assembly of a protein…

Q: Explain the importance of differential gene expression. Why don't cells and organisms simply express…

A: Gene expression is the process by which a gene's information is used to create a functional gene…

Q: Define Genome-wide analysis of allele-specific expression ?

A: Allele-specific expressions occur due to preferential expression of a parental allele in a hybrid.…

Q: Epigenetic markers tell your genes to switch on or off. What are two environmental factors that can…

A: While most environmental exposures affect somatic cells and do not allow for transgenerational…

Q: explain which controls over gene expression are likely to be very brief, which may be long lasting,…

A: DNA and RNA are the types of nucleic acids that carry genetic information. DNA is transcribed to…

Q: Phenotypes can be controlled by many processes besides the actual genotype present.  Explain one…

A: Epigenetics is the study of heritable phenotype changes that do not involve alterations in the DNA…

Q: The phenotype of a heterozygous mouse (Aa) is agouti.  The agouti banding pattern is due to altered…

A: * Homozygous dominant and Heterozygous will produce agouti that is AA or Aa respectively  and the…

Q: Define about expression QTLs (eQTLs) ?

A: The genes can be associated with simple or complex traits. The genes decide the nature of traits and…

Q: Define about random monoallelic expression ?

A: Genes are carriers of hereditary in organisms. A gene is a DNA sequences having two alleles in it…

Q: What is the relationship between beta-amyloid and the protein APP? How does the APP protein differ…

A: It is a progressive neurological disorder that causes the brain to shrink and brain cells to die.

Q: ABO blood groups: What happens if the wrong blood type is transfused?  What antigens from the ABO…

A: There are four different types of blood groups according to ABO system. Blood group A  Blood group B…

Q: When the expression of alleles are affected by the presence of other genes,such as sickle cell trait…

A: If a person is a carrier of sickle cell anemia then half of the RBC of the individual are…

Q: The human body contains many distinct cell types yet almost all human cells contain the same genome…

A: The human body contains many distinct cell types yet almost all human cells contain the same genome…

Q: What are the similarities and differences between a polyQ and a non-polyQ disease and how would we…

A: In this question, we have to give the similarities and differences between polyQ and non polyQ…

Q: Coat color in labradors is determined by alleles of two unlinked genes, B and E. The coat colors…

A: In the given situation, the determination of coat colour in labradors is governed by two independent…

Q: Name six different levels at which gene expression might be controlled.

A: The encoding of proteins by a gene that regulates cellular functions is known as gene expression.…

Q: How is the expression of PTGS1 and PTGS2 different?

A: The prostaglandins (PGs) are a group of lipids that are formed at the site of injury, tissue damage,…

Q: In detail explain what is gene expression and central dogmas of genetics? What are the steps…

A: GENE EXPRESSION : Process by which information on DNA is converted into Functional product like…

Q: explain how the deletion of the same set of genes can result in such different diseases. The example…

A: Imprinting is an epigenetic phenomenon connected to Prader-willi syndrome (PWS). A foetus typically…

Q: why the negative control sample (from an unaffected individual) only produced one band.   b.…

A: Huntington's Disease It is a rarer disorder where the brain cells or the neurons starts degenerating…

Q: In your own words, explain epigenetics. What is it? What are the main epigenetic marks? What do they…

A:

Q: Discuss what message does a gene provide? How is the language of the gene expressed?

A: The simplest physical and functional unit of heredity can be defined as a gene. DNA is what makes…

Q: What

A: Genomic imprinting:- A phenomenon in which expression of an allele in offspring depends on whether…

Q: Differential gene expression describes how... (Choose the answer the best illustrates the definition…

A: The expression of genes in for transcription that is the production of RNA from DNA. After the RNA…