Defects in the excision  repair process may result in : A. Mutations B. Okazaki fragments C. Excess DNA polymerase activity D. Shortened telomeres

Q: . You examine a 10-month-old infant who has numerous scaly and ulcerative skin lesions, premalignant…

A: Postreplication mismatch repair - it is a system for recognizing and repairing erroneous insertion ,…

Q: linkage disequilibrium

A: a) Linkage:  Linkage is the phenomenon of certain genes staying together during inheritance…

Q: 88) For The DNA polymerase enzyme: one option is incorrect a. Can work in the nucleus only b. Can…

A: Answer is d

Q: Explain how nucleotide incorporation errors by DNA polymerase can be repaired, and the role of…

A: DNA replication is a crucial process in the cell-division. It maintains the chromosome number inside…

Q: Define the following terms:a. hypochromic effectb. DNA denaturationc. restriction endonucleasesd.…

A: Recombinant DNA is made by combining two or more DNA from other sources. The process depends on the…

Q: Define base excision pair

A: Base excision repair can be defined as the mechanism in which DNA correction is done by correcting…

Q: Dr. A. Zion wants to study the flight gene of birds. In order to study the DNA, he must first…

A: Genes are the sections within the long DNA molecule.  To study DNA, you first have to get it out of…

Q: Explain the connection between defects in DNA repair systemsand the inherited human disease…

A: Genetic disorder It is also called as inherited disorder and is caused due to, Chromosomal…

Q: Describe in detail three spontaneous lesions that can lead to mutations. Give examples.

A: Three spontaneous lesions are depurination, deamination, and transversions. 1. Depurination occurs…

Q: a. Explain whether or not DNA polymerase from a mesophilic bacterium could be used successfully in a…

A: A)- In a mesophile optimum condition would allow the microbe to replicate at it maximum amount…

Q: which of these describes the symptoms of the disease(s) caused by mutations in this gene…

A: Mutation in the following gene i.e. XPA gene, causes malfunctioning of DNA repair mechanisms of our…

Q: The HIV virus produces copies of its genome through:     A. DNA replication     B. Reverse…

A: HIV (human immunodeficiency virus) is a type of RNA virus that affects the person's immune cell.…

Q: How can you treatment for the genetic disorders by using gene therapy?  Please answer at your own…

A: Gene therapy is a technique for correcting imperfect genes responsible for disease development. Gene…

Q: Why is it that the line of treatment for a genetic disease is different from infectious diseases?

A: A disease is a disorder that causes changes in physiological functions and result in specific sign…

Q: Discuss potential side effects of gene therapy.

A: Gene therapy is an experimental technique that uses genes to treat or prevent disease. This…

Q: DEFINE THE FOLLOWING: 1) restriction enzyme 2) plasmid 3) recombinant DNA

A: Ans 1) Restriction enzymes are enzymes that are isolated from bacteria that can cleave…

Q: Discuss about DNA damage response system

A: Due to some internal or external factors, the DNA of the cell may undergo certain alternation in its…

Q: What are some of the dangers of (and precautions against) recombinant DNA technology?

A: Recombinant DNA (rDNA) technology involves the joining of DNA molecules of two different organisms…

Q: 4) The laser allows us to: a. Specify the region of DNA damage b. Vary the amount of DNA damage c.…

A: Laser micro-irradiation, along with advanced live-cell microscopy, are used to study cellular and…

Q: What are the essential differences between base excision repair and nucleotide excision repair and…

A: Nucleic acids are made up of nucleotides, which are the basic building blocks. Long chains of…

Q: Write down the name of one genetic disease that has the potential to be cured through gene therapy.

A: Genetic diseases are the disorders due to defective genes present in an organism. The  genes present…

Q: A i. crossing over ii. biomarker a. Еcorl b. Recombinant iii. Gene-of-interest iv. restriction…

A: We know that crossing over is the major event during meiosis which leads to variations among…

Q: Which of the following DNA repair systems may involve the removalof a segment of a DNA strand?a.…

A: Answer is b.)  Nucleotide excision repair.

Q: Which DNA polymerase in prokaryotes is involved in the replacement of primers with deoxynucleotides?…

A: DNA polymerase is the enzyme that catalyses the replication of DNA. DNA polymerase cannot synthesise…

Q: utline the four broad classes of chemical damage to DNA.

A: Epigenetic mechanisms are described in detail. Multiple biological processes that affect epigenetic…

Q: Link the technique to the correct enzyme.…

A:

Q: _____ can correct a genetic defect in an individual. a. Cloning vectors c. Sequencing b. Gene…

A: Biotechnological perspectives are needed for developing new insights into the branch of life…

Q: ) Base excision repair requires polymerases. B.) In DNA repair by excision, the non-damaged strand…

A: Solution : Correct option is d

Q: A. Somatic cells are aslo called B. In irder to clone a gene,

A: A Somatic cells are also called Body cells .  Any other cells other than gametes are called somatic…

Q: Compare and contrast the action of DNA damaging agents that lead to: 1. Point mutations . 2.…

A: 1. Point mutation... Point mutation is the single nucleotide mutation in DNA. In this mutation…

Q: Why is DNA pol III still a thing, given that it lacks some of the functionality of DNA pol I - why…

A: The Central Dogma concept is a very important part of Molecular Biology. It states that "DNA makes…

Q: Describe any 5 types of mutation (except to loss of function and gain of function).

A: Mutation can be defined as a heritable genetic change in the genetic material of an organism,that…

Q: Contrast the various types of DNA repair mechanisms known to counteract the effects of UV radiation.…

A: A variation is an adjustment in a DNA grouping. Changes can result from DNA duplicating botches made…

Q: Enzymes or proteins involved in DNA repair include a. RAD52 b. RuvA c. UvrA d. MAPK

A: DNA repair is considered as a process in which any kind of damages is eliminated out.

Q: Explain endogenous and exogenous sources and how this relates to dna damage repair and recognition.…

A: Approach to solving the question: Detailed explanation: Examples: Key references:(1)…

Q: #10) Why are diseases of the blood simpler targets from treatment by gene therapy than are many…

A: Gene therapy is an experimental technique that uses genes to treat or prevent diseases. It involves…

Q: Explain why recipient cells do not successfully takeup plasmids during natural transformation.

A: The alternation of genetic material of cell that results from direct uptake and incorporation of…

Q: During a PCR reaction, all the following events occur except: A. Hybridization B. Binding of a 3’OH…

A: PCR : it is polymerase chain reaction, it is a technique of molecular biology which is used to…

Q: ____________ proliferate by cutting and pasting the original copy to another part of the genome,…

A: Genetic material is nothing but the sequence of nucleic acids which is called as DNA. It contains…

Q: The first mutation is thought to occur in utero in most cases of ALL diagnosed before age 5 years…

A: Acute Lymphoblastic Leukemia (ALL) is a type of blood cancer that affects white blood cells. It is…

Q: What are the genetic disorders that can be treated by using gene therapy?  Please answer at your own…

A: Genetic disorders are caused by whole or change in DNA sequence away from normal sequence .There are…

Viral Replication

The virus is acellular and considered non-living outside the host cell. The replication of the virus occurs only inside the living cells. Only a few genes are present in the smallest virus, whereas many genes are present in the largest virus. These genes encode specific viral proteins.