Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Consider how alternative splicing could allow many different protiens to be encoded by the same gene?
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- Suppose that a consensus sequence in the regulatory promotor of a eukaryotic gene that encodes an enzyme – let's call it finalexamase – was deleted. Which of the following effects would result from this deletion? (yes or no) 1. Finalexamase would have a different amino acid sequence. (yes or no)? 2. The mRNA for finalexamase would be abnormally short. (yes or no)? 3. Finalexamase would be missing some amino acids. (yes or no)? 4. The mRNA for finalexamase would be transcribed but not translated. (yes or no)? 5. The quantity of mRNA for finalexamase that is transcribed would be affected. (yes or no)?arrow_forwardLet's say there is an eukaryotic gene that has five exons and 4 introns. If the GU sequence at the 5' splice site of the third intron is deleted, describe how this is going to affect the expression of this gene. draw the mature mRNA too.arrow_forwardResearch has demonstrated that the composition of a gene’s promoter can affect alternative splicing of its RNA transcript. For example, promoters that are activated by certain transcriptional activator proteins cause one form of alternative splicing; when these activators are not present, a different form of splicing takes place. Propose some possible mechanisms by which the promoter could affect alternative splicing.arrow_forward
- Which of the following about the splicing in posttranscriptional processing is NOT true? a. In bacterial, the genes coding for polypeptides are interrupted by non-coding regions. O b. O C. O d. Introns in eukaryotic hnRNA must be cut out before mature mRNA can be used for protein synthesis. Alternate splicing can lead to tissue-specific proteins. Splicing can lead to multi-domain proteins.arrow_forwardWhich of the following mutations in the protein-coding region of a gene is more likely to lead to complete loss of function of the encoded protein: an insertion of six nucleotides or a deletion of two nucleotides? Briefly explain your answer.arrow_forwardUsing the transcription unit diagrammed below, in which exons are represented by blue boxes and introns are represented by the connecting lines. You discover a single base deletion in region E of this DNA sequence. Regarding transcription, this mutation will likely: 1.) Result in an alteration to the mRNA sequence. 2.)Have no effect on transcription or the mRNA sequence 3.)Prevent transcription at the TATAA box 4.) Result in an increase or decrease in the amount of mRNA transcribedarrow_forward
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