Choose whether the following compound will react faster or slower than benzene for an electrophilic aromatic substitution reaction. [ Select ] Then determine where the electrophile will be added on the ring. [ Select ]

Determine whether the following reaction is an example of a nucleophilic substitution reaction: O" Molecule A + NO₂ Molecule B NO₂ + H

Which of the following below would be considered a good Lewis Acid/Electrophile? A) OCH3 B) BF3 C) SCH3 D) CH3OH E) all of above

Substitution reaction

When the molecule reacting with the electrophile is a strong nucleophile and a strong base, the substitution reaction is favoured when There is the least amount of crowding (steric hindrance) around the alpha carbon There is the most amount of crowding (steric hindrance) around the alpha carbon The leaving group is a strong base

Fill both dashes in the paragraph  Compounds containing a phenol group may work as ANTIOXIDANTS to prevent free radical damage.  This is accomplished when a free radical (or UV light) encounters a phenol group, turning the phenol group into a radical.  However, contrary to typical radical behavior, the structure of the phenol radical can neutralize (or quench) the unpaired electron.  Specifically, the phenol structure neutralizes (or quenches) the unpaired radical electron by doing the following: taking the electron and ---------.  The correct name (or abbreviation) of an example compound (discussed in the lecture videos) containing a phenol group with antioxidant properties is: ---------.

Identify the electrophile in the following electrophilic addition reaction step. Explain your choice.

Consider the following reactants: H₂O Would substitution take place at a significant rate between these reactants? Note for advanced students: you can assume that the reaction mixture is heated mildly, somewhat above room temperature, but strong heat or reflux is not used. If you said substitution would take place, draw all the major products in the upper drawing area below. Be sure you use wedge and dash bonds where necessary, for example to distinguish between major products. If you said substitution would take place, also draw the complete mechanism for one of the major products in the lower drawing area below. If there is more than one major product, you may draw the mechanism for the production of any one of them. Note: be sure you show all the steps in your mechanism. A good check is to make sure the final product of your mechanism is a stable molecule that could be isolated and purified. Major Products: Click and drag to start drawing a structure. yes no X 9, X :0 G

Consider the structures of the carbocations formed by ortho attack of the electrophile, "NO, on the given starting material. Draw all resonance structures for the carbocation formed by ortho attack of the electrophile NO on the given starting material. If applicable, include the resonance structure in which π bond electrons "move" to the more electronegative atom as a lone pair. Be sure to include all charges and relevant lone pairs. Which resonance structure is the most unstable? Part 1 of 2 :0: NO2 A B :0: :Ö: а NO₂ C NO₂ + Draw all resonance structures for the carbocation formed by ortho attack of the electrophile "NO, on the given starting material. If applicable, include the resonance structure in which I bond electrons "move" to the more electronegative atom as a lone pair. Be sure to include all charges and relevant lone pairs.

Consider this nucleophilic substitution reaction.   1. Highlight the electrophilic carbon in red, and highlight the leaving group in blue. Highlight the atom in the nucleophile that will attack the electrophilic center in green. Only atoms need to be highlighted and not the lone pairs or formal charges. 2. Draw the product(s) of the reaction. Include all lone pairs.