Choose any/all that apply to the proton-motive force and ATP synthesis. The active pumping of protons through ATP synthase against their concentration gradient provides the energy needed for ATP synthesis. The ATP molecules produced from the pair of electrons provided by NADH have greater potential energy than the ATP molecules produced from the pair of electrons provided by FADH2. Each Beta subunit of ATP synthase has a distinct amino acid sequence that accounts for the three different active sites present in the enzyme. Rotation of the Y subunit creates conformational changes in the active sites of ATP synthase that drive the release of ATP from the enzyme. Inhibition of either ATP synthase or ATP translocase will stop flux through the electron-transport chain.

Choose any/all that apply to the proton-motive force and ATP synthesis. The active pumping of protons through ATP synthase against their concentration gradient provides the energy needed for ATP synthesis. The ATP molecules produced from the pair of electrons provided by NADH have greater potential energy than the ATP molecules produced from the pair of electrons provided by FADH2. Each Beta subunit of ATP synthase has a distinct amino acid sequence that accounts for the three different active sites present in the enzyme. Rotation of the Y subunit creates conformational changes in the active sites of ATP synthase that drive the release of ATP from the enzyme. Inhibition of either ATP synthase or ATP translocase will stop flux through the electron-transport chain.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter27: Metabolic Integration And Organ Specialization

Section: Chapter Questions

Problem 20P: Figure 27.3 illustrates the response of R (ATP-regenerating) and U (ATP-utilizing) enzymes to energy...

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Enzymes normally enhance the rates of biochemical reactions by preferentially binding and stabilizing the transition states rather than either the substrates or the products of a reaction. The F|-subunit of ATP synthase does not fit this norm so well as tight binding to ATP rather than a transition state is employed to make ATP. Explain the binding-change model of the mechanism of ATP-synthase. How and why is the proton-motive force used in the reaction cycle of ATP synthase?
Decide whether each of the following statements is true about leucine transaminase. It's an enzyme, and leucine is its substrate. It speeds up the rate at which leucine is converted to other substances. It's a small molecule, with a molecular weight around 50 mol If you were to write a chemical equation for certain biochemical reactions of leucine, leucine transaminase would appear on both sides. Otrue Ofalse Otrue Ofalse Otrue Ofalse Otrue Ofalse X
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Describe the conformational changes (including substrates that bind to the different conformations) that occur in the F1 domain of ATP Synthase that result from protons flowing through the Fo domain down their concentration gradient: