Choose a pharmaceutical drug and answer the following questions about the drug: What is the IUPAC chemical name? Who discovered it or what company discovered it and when (if available)? What does the compound look like? Provide a picture of the compound. What are the functional groups in the compound? What are the medical uses for the drug? What is the mechanism of action of the drug (how does it work to affect the disease or malady)? How is it usually administered (ex. IV, pill, etc.)? What are the potential adverse effects of the drug?

Take a look at this organic reaction: CH3- 0=0 C O NAD+ NADH CH₂_1-0 CH3—C−O + CO2 The reactant molecule is re-drawn in the drawing area below. Highlight in red any groups in this molecule in which carbon atoms are oxidized by the reaction. Highlight in blue any groups in which carbon atoms are reduced. If no carbon atoms are oxidized or reduced, check the box under the drawing area. _L_L- C CH₂ - No carbons are oxidized or reduced. Ć

Question 2: НО. HO,,, HO OH Salicilin HO Salicilin is the natural precursor of Aspirin (Acetyl Salicylic Acid). Aspirin synthesis (shown in the scheme below) begins with the hydrolytic release of Salicylic Alcohol from Salicilin under acidic conditions. After oxidation, Salicylic Acid is then acetylated to produce Aspirin. Acidic Hydrolysis HO HO HO Salicylic Alcohol НО. HO,,. Xp= OH HO Salicilin HO O OH Salicylic Acid Oxidation HO a) Provide a detailed arrow-pushing mechanism showing the release of Salicylic Alcohol from Salicilin. H₂O, H+ OH Salicylic Acid 4.9 HO HO Acetylation Salicylic Alcohol + НО. & HO,,, HO Aspirin b) In the empty box, provide appropriate reagents and reaction conditions necessary to convert Salicylic Acid to Aspirin. OH Aspirin OH OH Glucose OH

"Freebase" cocaine is made by: O all of these methods. O dissolving powdered cocaine in starch and water and boiling it. mixing powdered cocaine and water, and heating it in a spoon. combining powdered cocaine with ether and heating it.