Cholera affects millions of people around the world. It causes diarrhea,which can lead to dehydration and even death. Cholera toxin affects achloride transporter that secretes chloride ion into the lumen of thesmall intestine. How does cholera toxin lead to dehydration?A. The toxin turns off the transporter, so the negatively charged chloridepushes water into the lumen.B. The toxin turns off the transporter, and water follows the ion due toosmosis.C. The toxin turns on the transporter and water is actively transported withthe ion.D. The toxin turns off the transporter and water is no longer exchange for thechloride ion.

Cholera toxin also called as choleragen which is abbreviated as CTX, it is AB5 multimeric protein…

Answered: Cholera affects millions of people…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Cholera affects millions of people around the world. It causes diarrhea, which can lead to dehydration and even death. Cholera toxin affects a chloride transporter that secretes chloride ion into the lumen of the small intestine. How does cholera toxin lead to dehydration?