A patient came to a dental clinic with complaints of dry mouth and multiple dental caries lesions. In the course of collecting anamnesis, it was found that an allergic patient takes antihistamines that block the H2 histamine receptors of smooth muscle cells of the salivary glands. It is known that histamine is a mediator that stimulates the secretion of saliva. Explain the mechanism of action of these drugs if it is known that the next day after discontinuation of the drug, the patient's dryness disappeared. Q: what type of inhibitor the drugs are taken by? what is their classification according to the mechanism of action?

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A patient came to a dental clinic with complaints of dry mouth and multiple dental caries lesions. In the course of collecting anamnesis, it was found that an allergic patient takes antihistamines that block the H2 histamine receptors of smooth muscle cells of the salivary glands. It is known that histamine is a mediator that stimulates the secretion of saliva. Explain the mechanism of action of these drugs if it is known that the next day after discontinuation of the drug, the patient's dryness disappeared. For this: а) write the classification of inhibitors according to the mechanism of action b) indicate what type of inhibitors the drugs are taken by the patient; confirm your conclusion in writing c) guess what structure this drug may have d) give a picture illustrating the action of this type of inhibitors.

North Americans have among the highest rates of colon cancer in the world. Rates of type 2 diabetes and cardiovascular disease are also among the highest in the world. Give two reasons why these rates are so high, and explain how they could be reduced.