CHALLENGE PROBLEM 2 You are carrying out Beadle Tatum type experiments to analyze a metabolic pathway in Neurospora. You know that the precursor in the pathway is a molecule symbolized as P and that the product is a vitamin symbolized as Z. You are sure that the pathway from P to Zis linear and that the molecules W, X, and Y are intermediates. However, there may be other intermediates not yet identi- fied. You obtain 10 independent mutations that cannot grow on minimal medium supplemented with P, but can grow on minimal medium supplemented with Z. The 10 mutants fall into four classes that can grow (+) or cannot grow (-) on minimal medium supplemented with the nutrients W, X, or Y. The data are shown in the accompanying table. PW X Y Class I (mutant 5) Class II (mutants 1, 3, 4, 6, 7) Class III (mutant 2) Class IV (mutants 8, 9, 10) Draw a linear metabolic pathway with P on the left and Z on the right, in which each of the intermediates W, X, and Y is shown in the order in which it occurs in the metabolic pathway in the synthesis of Z from P. N + + + + + > | + +

CHALLENGE PROBLEM 2 You are carrying out Beadle Tatum type experiments to analyze a metabolic pathway in Neurospora. You know that the precursor in the pathway is a molecule symbolized as P and that the product is a vitamin symbolized as Z. You are sure that the pathway from P to Zis linear and that the molecules W, X, and Y are intermediates. However, there may be other intermediates not yet identi- fied. You obtain 10 independent mutations that cannot grow on minimal medium supplemented with P, but can grow on minimal medium supplemented with Z. The 10 mutants fall into four classes that can grow (+) or cannot grow (-) on minimal medium supplemented with the nutrients W, X, or Y. The data are shown in the accompanying table. PW X Y Class I (mutant 5) Class II (mutants 1, 3, 4, 6, 7) Class III (mutant 2) Class IV (mutants 8, 9, 10) Draw a linear metabolic pathway with P on the left and Z on the right, in which each of the intermediates W, X, and Y is shown in the order in which it occurs in the metabolic pathway in the synthesis of Z from P. N + + + + + > | + +

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter21: Photosynthesis

Section: Chapter Questions

Problem 8P

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