Organomagnesium compounds
The interaction of alkyl halide with Mg metal in a suitable ether solvent is the common method for the synthesis of the Grignard reagent.
Hydrolysis Grignard Reactions and Reduction
Organomagnesium halides are Grignard reagents. Francois Auguste Victor Grignard, a French chemist who received the Nobel Prize in Chemistry in 1912, created these highly useful reagents.
The endiandric acids comprise a group of unsaturated
isolated from a tree that grows in the rainforests of eastern Australia.
The methyl esters of endiandric acids D and E have been prepared from
polyene Y by a series of two successive electrocyclic reactions: thermal
ring closure of the conjugated tetraene followed by ring closure of the
resulting conjugated triene. (a) Draw the structures (including
stereochemistry) of the methyl esters of endiandric acids D and E. (b)
The methyl ester of endiandric acid E undergoes an intramolecular [4 +
2] cycloaddition to form the methyl ester of endiandric acid A. Propose a
possible structure for endiandric acid A.
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