Central self-tolerance in the immune system arises when maturing T cells in the thymus undergo apoptosis when they bind to self-antigens. Based on this information, what would MOST likely occur as the chick immune system develops? A. T cells would recognize transplanted quail somites as foreign and rapidly divide. B. T cells would recognize transplanted quail somites as foreign and undergo apoptosis. C. T cells would recognize transplanted quail somites as self and rapidly divide. D. T cells would recognize transplanted quail somites as self and undergo apoptosis.
A classical experiment studying the fate determination of stem cells in the developing embryo uses the transplantation of somites from one organism to another. In such an experiment, a scientist transplanted somites 20, 21, and 22 from the right side of the neural tube from five-day-old developing quail embryos into chick embryos. The transplantation was performed in two orientations so that the order of the somites was sometimes reversed.
Use the passage to answer the question.
Central self-tolerance in the immune system arises when maturing T cells in the thymus undergo apoptosis when they bind to self-antigens. Based on this information, what would MOST likely occur as the chick immune system develops?
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A.
T cells would recognize transplanted quail somites as foreign and rapidly divide.
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B.
T cells would recognize transplanted quail somites as foreign and undergo apoptosis.
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C.
T cells would recognize transplanted quail somites as self and rapidly divide.
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D.
T cells would recognize transplanted quail somites as self and undergo apoptosis.
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