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Briefly explain this statement -"Therapeutic drug monitoring of Warfarin" Please explain at your own words(500-600 words appropriately).
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- Write about Pfizer-BioNTech COVID-19 vaccine (Tozinameran) You must include the following information Chemistry of the drugs: Structure, physicochemical properties, (log P, pKa, & stereochemistry) and chemical properties and stability. Mechanism of action: (including the possible drug target interactions) in CoVid-19 Pharmacokinetic: Absorption, distribution (% plasma binding), chemical basis of metabolic pathways and elimination Pharmacological properties including side effect, ADR, drug interaction, precautions, dose and dosage forms Stability and storage conditions, as well as Brand namesDO NO INC de zeros at the end of decimal numbers. The problems and drug orders are presented for practice only, and actual prescribed factors. Order: Monocid 500 mg Supply: Monocid 1,000 mg Directions: Reconstitute with 2.5 mL of sterile water to yield 325 mg/mL Give: mL 4. Moving to another question will save this response. Type here to search EO 9Dose ordered garamycin 60 mg Im stock available gentamicin injection 40 mg/ml (20-ml vial) how many ml are need for the dose ordered?
- Match the following drugs with their pharmacologic classification (Column A), type of receptor interaction (Column B), and nature of drug mechanism (Column C).Type in the CAPITAL letter of your answers and separate them a dash (-). Be careful to not put spaces on your answers (example: A-A-A)INTERPRETATION OF RESULIS NEGATIVE: Two lines appear. One colored line should be in the control region (C), and another apparent colored or faded color line adjacent should be in the test region (T). This negative result indicates that the drug concentration is below the detectable level. POSITIVE: One colored line appears in the control region (C). No line appears in the test region (T). This positive result indicates that the drug concentration is above the detectable level. INVALID: Control line fails to appear. Insufficient specimen volume or incorrect procedural techniques are the most likely reasons for control line failure. Review the procedure and repeat the test using a new test panel. If the problem persists, discontinue using the lot immediately and contact your local distrībutor. READING OF RESULTS INTERPRETATION SONTROL TEST SAMPLEpropose a biomaterial-based drug delivery system for carrying targeted delivery of doxorubicin for the specific treatment of hepatocellular carcinoma via intravenous route (for human)
- Do not include zeros at the end of decimal numbers. The problems and drug orders are presented for practice only, and actual prescribed dosages factors. Order: Rocephin 500 mg IM Supply: Rocephin 1 gram Directions: Reconstitute with 2.1 mL of sterile water to yield 350 mg/mL Give: ML Moving to another question will save this response. Type here to search O E M 90 DELLExplain the term first-pass eject or hepatic metabolism of the drug. What effect does first-pass have on drug bioavailability and activity?Pharmacodynamic (PD) Response Biomarkers Instructions Group (https://www.ncbi.nlm.nih.gov/books/NBK326791/), a biomarker is used to show that a biological response has occurred in an individual who has been exposed to a medical product or an environmental agent. Match the pharmacodynamic/response biomarker on the left, with the related you can use internet search, FDA According to the FDA-NIH Biomarker Working treatment/disease on the right. Please note that and NIH websites, as well as the on-line library resources. Sweat chloride Response to warfarin treatment International Effect of enzyme replacement therapy for patients with mucopolysaccharidosis type 1 normalized ratio (INR) Response to a B-lymphocyte stimulator inhibitor in patients with systemic lupus erythematosus Viral load Urinary level of glycosaminoglycans Response to cystic fibrosis transmembrane regulator (CFTR) potentiating agents in patients with cystic fibrosis Blood pressure Response to antihyperglycemic agents or…
- Explain the term low therapeutic index.Write about Oxford–AstraZeneca COVID-19 vaccine (Covishield) You must include the following information Chemistry of the drugs: Structure, physicochemical properties, (log P, pKa, & stereochemistry) and chemical properties and stability. Mechanism of action: (including the possible drug target interactions) in CoVid-19 Pharmacokinetic: Absorption, distribution (% plasma binding), chemical basis of metabolic pathways and elimination Pharmacological properties including side effect, ADR, drug interaction, precautions, dose and dosage forms Stability and storage conditions, as well as Brand namesDescribe the enzymatic reaction of the protein epidermal growth factor. Include the specific reaction catalyzed by the protein. Enzymatic reaction is a physiologically relevant biochemical stimulus for the temporal and spatial control of drug release because: (1) the overexpression of specific enzymes is localized at diseased tissues.