Choose (+) if the following circumstances or situations will most likely result to production of intrinsic activity, if otherwise, choose (-). Dissociation of drug molecule from binding site

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 7.7P
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Choose (+) if the following circumstances or situations will most likely result to production of intrinsic activity; if otherwise, choose (-)

Choose (+) if the following circumstances or situations will most likely result to production of intrinsic
activity; if otherwise, choose (-).
+
Dissociation of drug
molecule from binding site
Formation of H-bonds
between drug and receptor
Presence of hydrophobic
interactions
Introduction of an antagonist
at receptor sites
High concentration of
competitive antagonist at the
binding site
Blockade of binding site due
to steric hindrance
Complementing shapes of
drug and binding site
Lack of affinity between drug
and binding site
Formation of an irreversible
drug-receptor complex
Conformational change
between drug and receptor
after binding
Transcribed Image Text:Choose (+) if the following circumstances or situations will most likely result to production of intrinsic activity; if otherwise, choose (-). + Dissociation of drug molecule from binding site Formation of H-bonds between drug and receptor Presence of hydrophobic interactions Introduction of an antagonist at receptor sites High concentration of competitive antagonist at the binding site Blockade of binding site due to steric hindrance Complementing shapes of drug and binding site Lack of affinity between drug and binding site Formation of an irreversible drug-receptor complex Conformational change between drug and receptor after binding
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